"Kventiax": instructions for use, analogs, reviews and

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2018-04-01 19:56:24

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Contains information about the drug “Kventiax” radar. Instructions for use of this tool is quite simple, but to comply with her important, so she posted in one of the oldest directories of medicines (it has been published since 1993!). The doctor who prescribed the drug, pay attention patients: the effectiveness of therapy is directly determined compliance with the instructions for use. The drug ‘Kventiax” as mark used them when taking adequate doses provokes relatively little negative effects, mainly observed only a weak negative response of the organism. Try to figure out how to use the medication correctly.

Important!

On the vast world wide web you can find a lot of information about how to use “Kventiax”. Indeed, the data is useful, allow you to get a General idea about the medicine, but are not the basis for the appointment of his own. Only a doctor can prescribe such a drug, and the pharmacy sell only when prescribed.

Before use must carefully read the manual for use ‘Kventiax”. It is likely that the manufacturer made some adjustments. The most relevant and accurate data is always enclosed in the packaging of the medication and require detailed study.kventiax instruction manual counterparts

General information

The First thing we can learn from the instruction on the application of “Kventiax», – it is an active component, whereby the tool shows a positive result. It has the name quetiapine. The medicine belongs to the group of antipsychotics and a variety of pills. The main substance present in one tablet in a concentration of from 25 to 300 mg. the Exact amount indicated on the cardboard packaging that contains the blister with a drug.

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kventiax instructions for use of the radar

In addition to “Kventiax”, there are two more names of medicines based on the same active connection.

  • “Chetelat”.
  • “Seroquel”.

For counterparts “Kventiax" instructions for use, in General, similar with the described substance: it is also pills that need to drink in strict compliance with doctor-recommended scheme. Differences were observed in the efficiency of reception and characteristics of adverse reactions. Replace the ‘Kventiax” for the same medicines without a doctor's advice is not even worth to save. If you can not acquire prescribed remedy, you need to book another appointment to the doctor and find out what it can be replaced.

Medicine: what is it and why?

As you can see from the instructions for use, the ‘Kventiax” based on quetiapine. This antipsychotic drug class of atypical. In medical practice, widespread its use in various forms of schizophrenia, including acute course chronic varieties of the disease. You can resort to the “Kventiax" for bipolar disorder and a number of other pathologies often encountered in the practice of psychiatrists.

Receiving antipsychotic affects neurotransmitter receptors in brain. As indicated in the instructions for use, “Kventiax” characterized by an affinity to the receptors of dopamine, serotonin, histamine, and adrenergic. It is noted that the drug has a strong effect on the receptors 5-HT2, especially in comparison with the inhibition of the D1 dopamine receptor, D2. It is noted that “Kventiax” has no pronounced effect with respect to the GABA receptor, benzodiazepine, cholinergic muskarinovymi.

How it works?

As you can see from the instructions for use "of Kventiax" (photos of the drug presented in the material), at the moment there is no absolutely accurate and reliable information, explaining the features of influence of the active component on the human body. Medical practice shows that extrapyramidal (observed very rarely), antipsychotic the results of the application due to the combined antagonistic effect on receptors in brain. However, we have to admit: “Kventiax” is not the only drug on the modern pharmaceutical market, the mechanism of action which does not have a clear base, it has yet to be explored.

kventiax instruction manual feedback about the drug

But the performance, as can be seen from the reviews, instructions for use "of Kventiax”, beyond doubt. This is confirmed by specific tests carried out with the aim of identifying antipsychotic efficacy, and the numerous responses. As noted by the patients that the doctor recommended to undergo treatment with this drug, in “Kventiax” provokes rather mild side effects which usually pass in the first time after the start of therapy. In this respect, the tool is preferable to many other antipsychotics with similar efficiency to the human body. At the same time it cannot be denied that some of the ‘Kventiax” is not appropriate.

Tested and proven

One of the key tests used to confirm the effectiveness of acceptance "of Kventiax”, is called the study of conditional avoidance. The technique showedthe performance of the funds during the therapeutic course. In the course of specialized clinical trials also failed to reveal that the active component of the drug equally copes with negative and positive manifestations of schizophrenic disorders. As you can see from the reviews, the instructions for use, the ‘Kventiax" (and it is confirmed in the official order) is comparable in its effect with drugs on haloperidol, chlorpromazine, at the same time shows the characteristic of these formulations negative side effects.

At the same time, we know that drug may cause drowsiness. According to the doctors, instructions for use "of Kventiax” contains an adequate explanation of this fact. The drug influences the receptors of histamine, which leads to similar effects on humans. Take into account this fact is necessary during the course of people forced to work with machines, machines, other equipment and tasks that require high speed response. These relate to management of vehicles.

Advanced research methods

As part of the development of the drug have been some animal studies. The main objective was to identify extrapyramidal symptoms. The information provided was taken into account and included in the instructions for use "of Kventiax”. The reviews about the drug contain the opinion that the listed possible reactions do occur, but very rarely, and most patients with such a response of the organism does not occur.

kventiax usage instructions reviews of doctors

Experiments involving animals has shown that the application of dosages, which allows to achieve the blocking of a number of receptors for dopamine, may be accompanied by catalepsy only in very weak form. It is known that the active substance is a selective action, especially with regard to the mesolimbic system. Confirmation of this conclusion – a selective decrease in the frequency of the bit a10 neurons compared to A9. In the study of drug efficacy in monkeys have established that the probability of occurrence of dystonia is minimal.

Research and effects

As you can see from the instructions for use, the ‘Kventiax CP” does not increase the concentration of prolactin. Clinical studies in which patients repeatedly used the fixed dosage showed that the number of prolactin coincides with the observed in the control group a placebo and those who had used the substance in a dosage range of permissible concentration.

Additionally conducted three studies involving a comparison of the effectiveness of the tools in the background of the groups the placebo. Information on the results are also recorded in the instructions for use ‘Kventiax CP”. Used a variety of dosages, from the minimum to 750 mg per day. The results have shown that extrapyramidal symptoms with equal frequency observed in all groups of patients. Tests showed the dependence of the frequency of extrapyramidal symptoms, when you are linking "of Kventiax” and cholinergic. Also, the study revealed that the best effect shows with daily use twice a day. The effect on the receptors lasts up to 12 hours during normal operation, the internal systems.

What happens in the body?

Instructions for use of the drug “Kventiax" (200 mg or any other dosage) refers to the increased absorbability of the active ingredient after oral use. Not observed based on bioavailability from meals. In the plasma component of blood is the greatest concentration of active component reaches after half an hour after receiving medication in food.

kventiax usage instructions 200 mg

Up To 83% of the active substance, as stated in instructions for use "of Kventiax" (200 mg and other dosages) quickly forms a strong bond with plasma proteins. Metabolism mainly occurs in the liver, the biological transformation due to oxidative reactions, sulfookislenie. The studies identified that the main metabolic enzyme-CYP3A4. Produced in the metabolism of compounds have pharmacological effects on the human body.

The half-life – seven hours. To five percent leave the body in an unchanged form. 73% of products of metabolic reactions derived urinary system, 21% - with the feces.

Pharmacokinetics

According to reviews, analogs «Kventiax” (the instructions for use may look slightly different) have similar effect, if based on the same active component, but the drugs from the group of neuroleptics, as the basic compound includes other substances that are (often) more severe adverse reactions. This is largely due to pharmacokinetic differences. For “Kventiax”, as studies have shown, a characteristic linear process, if the tool is used in a therapeutic dose. Not observed specific reactions based on gender or race.

drug kventiax usage instructions 200 mg

On average, clearance of the active component is observed below one-third, and sometimes half in the treatment of older people. This requires an adjustment of the treatment program if the patient is older than 65 years.Plasma clearance is reduced by a quarter in severe renal failure, hepatic disorders including cirrhosis, triggered by addiction to alcohol. At the same time, there are cases when the clearance in people with such disabilities remains at a level characteristic of a person with a healthy kidneys, or liver.

When to apply?

The Manufacturer recommends to use the tool with the following diagnoses:

  • Schizophrenia;
  • Depressed, manic pathology associated with bipolar disorder first, second class;
  • Psychotic organic disorders.

How to use?

The Best effect is observed when splitting the daily dose into two doses with equal time intervals between them. The use of funds does not depend on the arrivals in the digestive system of food. For adults at the beginning of the therapeutic course (4 days) it is recommended to use ‘Kventiax” according to the following scheme: 50 mg, 100 mg, 200 mg, 300 mg. of the Fifth day and other course-titratable dosage is in the range of 300-450 mg.

drug kventiax instruction manual

As practice shows, sometimes sustained clinical effect it is possible to achieve 150 mg daily, but some patients pronounced effect gives only the constant use of 750 mg.

At therapy elderly medication is allowed only under the condition of controlled, careful use and regular checking of vital functions of the body. The initial dosage is 25 mg, daily gain varies from 25 to 50. It is necessary to increase the number “Kventiax” on a daily basis, yet fail to achieve brilliant results. Experts note that in most cases the effective dose is significantly less than for younger patients. For children, teenagers ‘Kventiax” use is not recommended, as there have been no official studies, allowing to establish side effects, safety of use of medication. There are no exact data about the effectiveness of the drug in the treatment of minors.

If the treatment given to patients with impaired liver function, kidneys, starting dose – 25 mg Daily increased to 25-50 mg until will be a stable positive effect of the program. Usually the patient is additionally administered a regular research body with the aim of preventing serious violations related to overdose on a background of the inability of internal organs to process the received drug.

Negative effects: what to expect?

For reviews of cardiology, instructions for use "of Kventiax” although it contains an indication of a negative impact on the work of the cardiac system, many patients do not pay enough attention. The manufacturer notes that referenced side effects – the state identified in the comparison take the drug control groups and controlled placebo. Treatment of both categories was accompanied by a number of negative reactions, so in the official list includes only those for which the frequency was higher in comparison with the placebo group.

Noted that most often, patients complained about headache – faced with this nearly a fifth of the control group. Some develop fever, asthenic conditions, abdominal pain. Up to 2% of patients experienced a weight gain, lumbar pain, pain in the chest. It is known that the drug increases the drowsiness may contribute to anxiety provoking dizziness. There is a possibility of violation of the chair, the growth and activity of hepatic transaminases – the counts return to normal with continued therapy course. Up to five percent of patients are faced with leukopenia, neutropenia. Extremely small, but there is a risk of developing eosinophilia.

tool kventiax instruction manual

As you can see from the feedback of cardiology, instructions for use, the ‘Kventiax” may cause hypotension, arrhythmias of the heartbeat and hypertension. There is a possibility of pain in the ears, infections of the urinary tract, rhinitis, myalgia. Some patients experienced rash, and dry skin.

When not?

As you can see from the instructions for use, the ‘Kventiax” is not allowed if the patient characterized by increased sensitivity to any substance present in the composition of the medication. You can not use the medicine if the patient is undergoing preparations containing inhibitors of cytochrome. Among these compounds belong to medication:

  • Erythromycin;
  • Nefazodone;
  • ==.

The Restrictions imposed the use of antifungal drugs in asola and HIV protease inhibitors.

Special event: pregnancy and breast-feeding.

Were Not conducted specific studies to determine the severity of the application «Kventiax” in the period of carrying a child and breastfeeding. Currently employ the following approach: if necessary, use of neuroleptics with effect similar “Kventiax”, the doctor analyzes the possible risks for woman and fetus, compares with positive effects in the case of the therapeutic course, acquaints the patient with all the possible negative outcomes of medication and only with her consent and the obvious dominance of the positive aspectsrecommends taking this drug.

Unknown, selects whether the active component of “Kventiax” in human breast milk, in what quantity it occurs. If necessary, therapy course is recommended to switch to artificial feeding, avoiding breast. We carried out experimental studies which failed to establish the likelihood of mutations, and teratogenic, clastic influence of the active substances.

Special experiments

Additional studies were organized with the aim of identifying the influence of money on sexual activity. The experiments took place only on animals. As the results showed, decreased sexual activity, increases the length of time between heat and reduced the likelihood of pregnancy. Some laboratory animals were observed false pregnancy. The information obtained in the course of such research, not applicable to man directly, as the hormonal control of reproductive cycle has important differences, however, officially the information received must be taken into account, and the manufacturer is obliged to familiarize with it each receiving the medication. Information about the tests can be found in the instructions for use "of Kventiax”.

kventiax instructions for use photo

Heart disease and brain

If the drug is recommended to patient suffering from heart diseases or pathologies of the vascular system, must be very carefully to use the drug regularly to check the performance of vital organs. This is true for other conditions and diseases, which increases the risk of hypotension. It is known that “Kventiax” could trigger a violation of orthostatic form. The highest risk for the beginning of the therapeutic course, while there is a selection of the optimal dosage. Adverse reaction is more common in the treatment of older people than patients of young and middle-aged.

You Must very carefully apply the ‘Kventiax” with simultaneous use of drugs that increase the QT interval. This is especially true for elderly patients. If there are functional disorders of the liver, it also imposes certain restrictions on the ability of therapy with the use of “Kventiax”.


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BE: https://tostpost.com/be/zdaro-e/1107-kventiaks-nstrukcyya-pa-zhyvann-analag-vodguk.html

DE: https://tostpost.com/de/gesundheit/1104-kventiaks-anwendungshinweise-analoga-und-bewertungen.html

ES: https://tostpost.com/es/la-salud/1109-kventiaks-instrucciones-de-uso-an-logos-y-los-clientes.html

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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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