"Karotegin": instructions for use. Where to buy "Karotegin"? What pills "Karotegin"? The Analogues Of "Klarotadina"

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2018-03-27 19:36:19

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Allergic reactions – the topic is quite relevant, especially for parents. After all, every year the number of so-called "allergies" are constantly increasing. So today we will discuss the details of the drug "Claratin". Instructions for use will start our review of this drug. We recommend you to see it before use. Buy "Karotegin" at any pharmacy in your city and without a prescription.

pills klarotadina

When to apply

This drug can be used in allergic conjunctivitis, angioedema, in urticaria (acute, chronic, and idiopathic). Drug "Claratin" is also effective in the period year-round or seasonal rhinitis; allergic reactions that are caused by release of histamine; reactions to the bites of various insects; and in itching dermatoses. The list may be supplemented.

What's available

klarotadina usage instructions

We first Consider the drug "Karotegin"-syrup. Usage instructions it is given below. Dosage-5 mg/5 ml. Loratadine (active substance) one milligram per milliliter of syrup. Excipients: propylene glycol, sugar, benzoic acid, ethyl alcohol, citric acid, tropeolin, purified water, flavoring substances.

Sold in a bottle made of dark glass having a capacity of one hundred milliliters. This bottle is in a cardboard box. The kit also includes a special measuring spoon.

Now consider a pill "Claratin". One tablet features a ten milligram loratadine. Of excipients ­– MCC, lactose, calcium stearate, a glycolate, sodium starch. Placed in the contour of the package, each of which has seven or ten. In cartons can be from one to three packages of plates.

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Pharmacodynamics

This drug belongs to H1-antihistamine drugs, which do not have anticholinergic and Central effects. Starts to work within half an hour after eating and is valid throughout the day. It is important that chronic administration of this drug does not develop resistance to it. It should be noted that the substance loratadine and its metabolites are able to penetrate the BBB.

Pharmacokinetics

As for the suction, during the intake in the doses recommended by manufacturer, the main component of loratadin fairly quickly and fully absorbed into the bloodstream through the gastrointestinal tract. Concentration, which can already be identified, appear in the composition of the blood plasma fifteen minutes after consumption. As for the time to reach Cmax plasma loratadine, it varies from one hour and forty minutes to two hours thirty minutes.

But the time to reach Cmax of its active metabolite is almost three hours. Just keep in mind that simultaneous intake of food along with the medicine can slow the achievement of Cmax loratadine and its active metabolite in plasma for one hour. Thus Cmax of these substances is unchanged, and the food is unable in any way to affect the result.

Now about the elderly. "Karotegin" (the instruction on application notes) they can take without any special reservations about age. Just keep in mind that the time to reach Cmax is increased by one and a half hours, in contrast to young people. With regard to alcoholic liver disease, depending on the severity of the disease the time to reach Cmax is also increased.

In the blood plasma the content of loratadine with its active metabolite reaches most patients stationary level on the fifth day after admission. And the connection with plasma proteins – 97%.

Metabolism

claratin syrup usage instructions

Liver active substance loratadine metabolized, forming the active metabolite of descarboethoxyloratadine. This is due to the impact of the cytochrome P450 isoenzymes CYP3A4. The impact of the CYP2D6 isoenzyme of cytochrome P450 was also affected, though to a lesser extent. The present ketonazole, which is an inhibitor of CYP3A4, allows loratadine to turn into descarboethoxyloratadine. This happens due to the effect of CYP2D6.

Removal

Display product "Karotegin" (instruction manual also mentioned it) via the kidneys and with bile. The average T1/2 of the substance loratadine is eight hours and twenty minutes (the range can be from three to twenty hours). With regard to active metabolite, it is the average is twenty-eight hours (range can be from six hours forty minutes to thirty-seven hours).

The Average of descarboethoxyloratadine is seventeen hours and thirty minutes (range from eleven to thirty-eight hours). If we are talking about liver damage with alcohol, then T1/2 will increase along with an increase in the severity of the disease. But in patients who have renal failure and receiving dialysis, the pharmacokinetics are not particularly changes.

drug klarotadina

Pregnancy

Pregnant women should not take this drug as "Claratin" the children who are in the womb, can cause harm. If you want to use this drug in lactating mother, it is necessary to suspend breast-feeding for as long as treatment is completed.

Contraindications

As with other drugs, has contraindications and "Claratin". Instructions for use suggests that this drug should not be used if the patient has a hypersensitivity to any components of this drug. Pregnancy and breast-feeding are also circumstances in which this tool is not assigned and accepted. Patients who have hepatic insufficiency should take the drug "Karotegin" with caution.

Side effects

Now, let's talk about how can adversely affect this drug on the human body. Possible manifestations of disorders of the nervous system, namely anxiety, fatigue, hyperkinesis, excitation in children, drowsiness, tremor, paresthesias, depression, and amnesia. Subcutaneous fat and skin can react to components of medication dermatitis.

pills klarotadina

If we talk about the urino-genital system, it can be observed the change of color of urine, the patient may feel the urge to urinate, followed by painful sensations. May also develop vaginitis, dysmenorrhea and menorrhagia.

From the endocrine system of the potential violation. Weight can increase, the patient will feel thirsty, and also it may increase sweating. Musculoskeletal system may also undergo some irregularities in their work. This cramping calf muscles and myalgia, and arthralgia.

Digestive system can also suffer. Distortion of taste, diarrhoea or constipation, anorexia, gastritis, dyspepsia, increased appetite, flatulence and stomatitis – all of this has a chance to occur if you use the "Klarotadina".

Prone to failure, and respiratory system. Violations will occur in the form of bronchospasm, cough, sinusitis, and dry mucous membranes in the nose. Can also develop conjunctivitis, disturbed vision, there was pain in the ears and eyes. The cardiovascular system is also vulnerable to side effects, which can manifest as palpitations, high blood pressure, as well as its decline.

There are cases of allergic reactions manifested as angioedema, pruritis, urticaria and photosensitivity. Can also appear back pain, fever, dysphonia, chest pain, chills, blepharospasm, and pain in the Breasts.

As you can see, the side effects can be quite serious, so do not forget about it. Doctor's consultation is obligatory before the first drug intake and the event of the above problems yourself.

klarotadina children

Usage and dosage

The Syrup and pills "Karotegin" from what – clear. Now let's talk about how we should accept it. The medicines designed for internal use. Children who are over twelve years and adults the recommended daily dose is ten milligrams. Two scoops of liquid syrup or one tablet. But children from two to twelve years, body weight less than thirty pounds, it is recommended to take five milligrams. It is one scoop or half a pill. Daily dose should not exceed this figure. If weight more than thirty pounds, the dosage is the same as for adults.

Overdose

If you do not listen to advice and take the drug in large quantities, may occur in adults symptoms, which will now be listed. It tachycardia, headaches and drowsiness. In children, body weight less than thirty pounds, in case of overdose may cause palpitations and extrapyramidal symptoms.

If the patient is admitted overdose, you should immediately contact a doctor. It is also necessary to take measures to ensure that the drug was removed from the gastrointestinal tract and reduced absorption. This is done by inducing vomiting, gastric lavage and use of activated charcoal. In case necessary, can be symptomatic treatment. It should be remembered that the active substance loratadine can not be inferred from the body by hemodialysis. Also there are no data on the excretion of this element during peritoneal dialysis.

Interactions with other drugs

If you apply "Karotegin" in a therapeutic dose, potentiating the action of alcoholic beverages is not detected. And when you apply this medication such antibiotics as a "Cimetidine", "Erythromycin" and "Ketoconazole" will increase the concentration in blood plasma loratadine. This phenomenon does not manifest clinically, and has no effect on electrocardiogram.

There is evidence that the inductors of microsomal oxidations, which include ethanol, phenytoin, barbiturates, rifampicin,sikorin, tricyclic antidepressants, phenylbutazone, can reduce the effectiveness of this drug.

Special instructions

Patients who suffer from impaired liver function and with renal failure (glomerular filtration has a speed of less than thirty ml/min) the recommended initial dose of the drug "Karotegin" should not exceed ten milligrams (one tablet or two level measuring spoons of syrup) twice a day. It is also impossible to give this drug to a child whose age is less than two years.

Anyone who began to take this medicine should be abandoned for the entire period of treatment from doing any kind of potentially hazardous activities, require high concentration and psychomotor speed reactions.

Counterparts

claratin or claritin

It's Fair to say that not one of a kind is a drug "Claratin". There are analogues among domestic and imported drugs. Fairly common overseas "brothers" is a prescription drug claritin. Its properties are almost the same as by the aforementioned drug "Claratin". Price – that's the main difference. Overseas drug much more expensive. Domestic has a price depending on configuration. Thus, the package 7 PC will cost about 100 rubles., packings valium planimetric 10 x 3 - about 270 rubles., and syrup 100ml - about 135 rubles.

We're not here to talk about that it is better to use – "Karotegin" or "claritin". This is a private matter, and you should decide for yourself, buying cheap home-made drug, or to prefer more expensive foreign. But it is worth noting that over the years proved itself very good drug "Claratin". The analogues thus appear every day.

In any case, before you start taking these drugs and especially to assign their children, be sure to consult with your doctor. This will protect you from the possible negative consequences that may occur as a result of intolerance to medications, improper use or overdose. You should always remember that such effects can present a significant threat to your health or the health of your children and your lives.


Article in other languages:

AR: https://tostpost.com/ar/health/14120-karotegin-karotegin-karotegin-klarotadina.html

BE: https://tostpost.com/be/zdaro-e/25222-klarotadin-nstrukcyya-pa-zhyvann-dze-kup-c-klarotadin-ad-chago-tabletk.html

DE: https://tostpost.com/de/gesundheit/25241-klarotadin-anwendungshinweise-wo-kaufen-sie-klarotadin-was-die-tablett.html

ES: https://tostpost.com/es/la-salud/25268-klarotadin-instrucciones-de-uso-donde-comprar-klarotadin-de-que-la-p-l.html

HI: https://tostpost.com/hi/health/14143-karotegin-karotegin-karotegin-analogues-klarotadina.html

JA: https://tostpost.com/ja/health/14146-karotegin-karotegin-karotegin-klarotadina.html

KK: https://tostpost.com/kk/densauly/25204-klarotadin-oldanu-zh-n-ndeg-n-s-auly-gde-kupit-klarotadin-sodan-tablet.html

PL: https://tostpost.com/pl/zdrowie/25130-klarotadin-instrukcja-obs-ugi-gdzie-kupi-klarotadin-od-czego-tabletki-.html

PT: https://tostpost.com/pt/sa-de/25148-klarotadin-instru-es-de-utiliza-o-onde-comprar-klarotadin-a-partir-do-.html

TR: https://tostpost.com/tr/sa-l-k/25211-klarotadin-kullan-m-talimatlar-sat-n-almak-i-in-klarotadin-ne-hap-klar.html

UK: https://tostpost.com/uk/zdorov-ya/25186-klarotadin-nstrukc-ya-po-zastosuvannyu-de-pridbati-klarotadin-v-d-chog.html

ZH: https://tostpost.com/zh/health/14785-karotegin-karotegin-karotegin-klarotadina.html






Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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