Efficient antispasmodic "Papaverine hydrochloride"

The Drug “Papaverine hydrochloride” refers to myotropic means possessing a strong antispasmodic action. For many decades it is used to reduce tone and relax the blood vessels and smooth muscles of almost all internal organs. He has a pronounced hypotensive action. This drug widens the arteries, increases the volume of blood flow, particularly cerebral. This drug in high doses dramatically reduces the excitability of the muscles of the heart, and also contributes to the slowing of intracardiac conduction. Its effect on the Central nervous system slightly expressed, although at higher doses it has a sedative effect.

The drug “Papaverine hydrochloride” in such dosage forms:

- tablets for adults with 0.04 g (10 units);

- kids tablets of 0.01 g (10 units);

- 2% solution for injection (10 ampoules);

- rectal suppositories 20mg (10 units).

Indications for use are conditions such as spasms smooth muscle organs peritoneum in cholecystitis, renal colic; spastic colitis; disease; bronchospasm; pilorospazme; spasms of blood vessels located in the brain. In the treatment of angina means “Papaverine hydrochloride" is used for complex therapy with other drugs.

Contraindications for the use of this drug are:

Hypersensitivity, impaired liver function, glaucoma, children's age (up to 0.5 years). In old age you cannot take this drug because there is a risk of hyperthermia.

Means “Papaverine hydrochloride": instructions for use

The drug is 3-4 p. per day. Dosage for a single pill, vary depending on the age of the patient. Adults appoint single pill at 40-60mg. Children 0,5-2 g - 5 mg, 3-4 - 5-10mg, 5-6 L.-10my, 7-9 L. - 10-15mg, 10-14 L. - 15-20mg.

The Solution for injection is administered intramuscularly or subcutaneously. Injections 2-4 p. per day 1-2 ml. An intravenous drug is administered very slowly 20mg, after adding thereto 10-20ml sodium chloride (saline solution-0.9%). This procedure is best carried out under the supervision of a doctor. For patients aged one-time initial dose should not exceed 10mg. Often this drug is administered parenterally in combination with a variety of spasmolytic and analgesic drugs such as the drug "Morphine".

Candles with papaverine administered rectally, 2-3 times a day for 20-40mg.

The Drug “Papaverine hydrochloride” may cause side effects such as drowsiness, allergic reactions, ventricular premature beats, increased activity of hepatic transaminases, decrease in blood pressure, constipation, eosinophilia.

If overdose observed symptoms such as weakness, double vision, excessive drowsiness.

When you use this medication should observe special instructions, which recommend caution to use the drug debilitated and older patients; people with head injuries, hypothyroidism, disorders of the adrenal glands, kidneys and liver; tachycardia; shock.

The Drug “Papaverine hydrochloride” during pregnancy and during lactation should be avoided since efficacy and safety in these times is not installed.

During treatment alcohol is prohibited. Smoking during treatment reduces the effectiveness of the drug. While receiving funds "Papaverine" and "Dopegitom" significantly reduced the effect of the first.

Papaverine hydrochloride is included in several combination antispasmodics in combination with other medicinal substances:

- the preparation “Luporini” - phenobarbital;

- the drug “Papillon” - platifillina of hydrodata;

- drug ", Celadrin” - with kellin and atropine sulfate;

- the drug “Kelliverin” - with kellin.

- the preparation “Nikoverin” - with nicotinic acid.