The newest method of diagnosis of cancer. Positron emission tomography. PET scan

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2018-03-19 09:40:37

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Positron-emission tomography, or PET CT – the study of internal organs by the method of radioisotope diagnosis. PET scan is also called a two-photon emission computed tomography, due to the fact that this method relies on detecting pairs of gamma rays.

PAT is a modern method of early diagnostics of oncological, cardiological and neurological diseases. In Oncology PET is used for diagnosis of malignant tumors, the search for distant metastases and monitoring treatment.

Positron emission tomography features a high accuracy of the study, the minimal radiation load on the body, the opportunity to explore all the bodies in one visit. The study itself is completely painless.

PAT, unlike any other research methods, considering the anatomical features of organs and tissues of the ongoing chemical processes. For cancer chemical processes change, it can be seen as a change in color and intensity of processes that are different from the norm.

Thus, thanks PAT began to see the cancer process long before a tumor is formed. Ultrasound, CT, MRI can detect a problem only when the tumor has already appeared and reached a certain size (for modern MRI machine at least 1-2  mm).

PET also will help to determine malignant or benign, this tumor, which is especially important when there is no possibility to obtain biopsy material.

PAT registers the flow of blood in the tissues and the consumption of tissue glucose and oxygen. In the patient's body is injected a certain amount of radioactive drug (radioactive glucose). Radiation from radioactive glucose  registers the special  scanner, which transfers all information into the computer. The computer processes and visualizes it.

Cells with high metabolism consume more glucose. That's what cancer cells are different from the usual. The more radioactive the drug enters the tissues, the brighter they appear on the resulting picture. Such areas are called “hot”. Conversely, the smaller the seized drug, the dimmer the image, such areas are called “cold”.

The Metabolism of malignant tumors is significantly higher than in healthy tissues. Therefore, malignant tumors produce a more vivid, “hot”, picture.

Very radioactive glucose is falling apart in less than a day and completely eliminated by the body.

Due to the fact that the PET scan covers your whole body entirely, you can make the most of this operating plan. This will remove all the affected tissue, if possible in each case. Which in turn will significantly reduce the risk of further relapse.

Using PET it is possible to accurately establish the stage of cancer, to see whether the affected lymph nodes before they started to increase. This allows the use of anti-cancer therapy significantly more effective.

At the end of chemotherapy and radiation therapy PET is used to determine the effectiveness of the treatment.

PET scan can detect metastases then  when other diagnostic methods are still not able to do so.

For example, examination of the lungs using x-rays can in the case of shading can only cause suspicion of the presence of metastases. Confirm their availability may either traumatic puncture tissue or PET, but the PET scan will determine the size of metastases and detects the spread of cancer cells in the early stages of the disease.

In contrast to scintigraphy using radioisotopes, the image of the PET study of three-dimensional, which gives the opportunity to estimate more accurately the picture of the disease.

The study Itself is conducted like this: the patient lies on a couch which slides inside the machine. The unit itself is similar to a short pipe. The procedure lasts from an hour to an hour. Before that the patient receives inhalation or intravenously specially prepared radioactive drug.

Contraindications for positron emission tomography a little. PET scan is contraindicated in pregnant and lactating women, as well as those patients who are not able to calmly, without any movements, valiati the time required for the study.

Positron emission tomography  the study is quite expensive. It costs from 50 000 rubles. In Russia devices for such research is only in major cities.

Of Course, there is no sense in having a PET-study as a preventive examination of a healthy person. It's enough regularly to do the analysis for tumor markers.

If the nature of the tumor is slow to metastasize, in this case, you can also restrict tumor markers or other tests and regular medical examination by a medical oncologist.

If the tumor was removed at a later stage and prone to rapid metastasis, then it makes sense to do a PET study. If the apparent cost of this study, the patient receives the result the whole picture of what is happening in his body changes. Based on this, the doctor may choose a more gentle and less costly method of treatment.

At current prices for medicines, PET scan, in many cases, pays for itself and allows you to save money on drugs much more than the cost of the study itself. In addition, neoplastic processes,  thanks to PET research, will be detected and stopped long before the can be diagnosed by other standard methods. Consequently, they will cause the patient much less harm.

And in the case of different kinds of lymphoma PET scan in the reliability simply nothing to replace. Other methods studies here will significantly give PET diagnosis, both accuracy and completeness, and speed of detection of metastases.

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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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