"Goserelin": instructions for use and reviews of doctors

Unfortunately, oncological pathologies of the genital organs, as well as problems with the reproductive system of both men and women, no surprise. If you do not deal with these diseases, the person can die. "Goserelin", the instructions for use which must be studied by the patient, and is intended for the treatment of such diseases.

Form of release and action features

So this drug is a synthetic substitute for the gonadotropin-releasing hormone. Long-term use of this medication reduces estradiol in women and testosterone in men. This helps to reduce the growth rate of malignant tumors of the prostate, breast, uterine fibroids or completely stop it.

Regarding the form issue, "Goserelin" (instruction manual is packaged with the medicine) sold at the depot-capsules syringe-applicator with protective mechanism. Their capacity is 3.6 mg. you can Also find the drug in capsules prolonged action, introduced under the skin. Their capacity in this case is 10.8 mg. They can also be purchased in a special syringe applicator, are equipped with a protective mechanism.

The Drug has a high oral bioavailability. The maximum concentration in blood is reached after 1.5-3 hours after ingestion depending on the sex of the patient. As for the composition, goserelin itself is the main active substance.

Indications for use

So, in order to start taking "Goserelin," the instruction manual includes the following indications:

• Prostate Cancer in men.
• Cancer of the breast in women who are in reproductive or premenopausal age.
• Endometriosis of the uterus.
• Surgery, which requires advance preparation - the thinning of endometrial layer.
• Uterine Fibroids.
• The Suppression of the functional activity of the pituitary gland in the event of a future artificial insemination.

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What contraindications exist?

Like any medications, have contraindications to the drug, and "Goserelin". Instruction manual warns about these restrictions on this medication.

• Too high sensitivity to the drug.
• Allergic reaction.
• Children up to age 14 years.
• Breast-Feeding.
• Pregnancy (even if it continues, the fetus may occur later pathology of fetal development).
• Compression of the bone marrow.
• Obstruction of the ureters.

Features

If the patient needs to use the "Goserelin", instruction for use (duration of use is strictly determined by the doctor) needs to be carefully examined. It contains information on such characteristics of: capsule is intended for subcutaneous injection. Its location - anterior abdominal wall.

If you are treatment of gynecological diseases, to accept the capsule should be every month. Dosage is 3.6 mg. To combat prostate cancer a man is introduced to 10.8 mg every 12 weeks.

We must Not forget that the first weeks of therapy being of the patient greatly worsens, since the level of hormones increases. This is a normal reaction to ingesting the drug.

The Duration of treatment is determined individually. Gynecological pathologies it can be no more than six months. It is important to remember that if the patient is assigned "Goserelin", the statement does not provide for the passage of re-treatment. The fact that the drug helps to reduce bone density and osteoporosis.

If the ingestion of the capsule was for some reason omitted, it is necessary to implement it as soon as the patient remembered it. Women who missed the regular medication, there is a risk of uterine bleeding.

Some adverse reactions may occur?

If the patient needs a long time to take such drug as "Goserelin", instruction and reviews from other patients will provide an opportunity to understand how it works. Of course, everyone will be wondering what side-effects may cause the medicine presented.

In males can result in such reactions:

• Reduced potency and libido.
• Swelling of Breasts and soreness (not often).
• Impaired patency of the ureters.

In women, however, can appear the following side effects:

• Increased sweating.
• Frequent shifts of mood and depressive state.
• Headache.
• Dry mucous membranes of the genitals.
• Strong reduction of libido.
• Demineralization of bone tissue, leading to bone fragility.
• Change the size of the Breasts.
• Menopause (in most cases, monthly bleeding will not be restored).

Common to both sexes are the following side effects: skin rash, infection of the nose, increaseblood pressure, heart rhythm disturbances.

Special instructions, interaction and feedback

So, if the patient must take the drug "Goserelin", the instruction (the drug is already known) gives the following special instructions:

• Capsules cannot be taken in conjunction with alcohol as it increases bone demineralization.
• Should Not together the drug you to drink anti-convulsants, and glucocorticoids.

As for the reviews, they say a lot about a large number of side effects and bad health in the first weeks of treatment. Not all patients a drug helps, although in most cases it is still effective.

If the specialist believes that the patient should take "Goserelin", instruction for use (reviews of doctors must be taken into consideration) should always be at hand in the patient throughout the treatment period. The specialists are unanimous in their opinion: despite the large number of adverse reactions, which occur in almost every patient, the drug is quite effective.

Special considerations

There are situations where after taking the drug should contact a doctor. For example, if:

• Started to show signs of increased intracranial pressure.
• Showed signs of hemorrhage in the pituitary gland: a sudden and severe headache, problems with vision, dizziness, confused speech. These symptoms can appear 2 weeks after the start of therapy.
• There are signs of compression of the spinal canal or problems with the urinary tract. This usually indicates pain in the lumbar region, too difficult movement of the upper and lower extremities, blood in the urine. Urination is painful.

There are also some facts that need to be considered before starting treatment:

1. The History of the patient, which takes into account the presence of osteoporosis, high cholesterol levels in the blood, as well as the presence of uterine bleeding of unknown nature, of thrombosis in the patient and his relatives.
2. The ability of a person to Smoking, because this habit contributes to the formation of blood clots.
3. The patient's Desire to have a baby soon or have a pregnancy.
4. Taking any medicines, even those sold over the counter without a prescription. It is important to tell the doctor about all biological supplements that are taken, and also herbal decoctions, which are used in the treatment.
5. Allergic reactions to any drugs.

Features of storage and counterparts

Like any other medical drug, "Goserelin" should be stored at room temperature, in a place that is well protected from UV rays and children.

If the patient is not possible to accept "Goserelin", instruction for use (counterparts can deal with the problem) advised to consult a doctor. Especially given that the drug has a high price - from 8000 RUB. per syringe. Among analogues it is possible to note "Zoladex", "Buserelin".

That all the features of the presented tools. Be healthy!