For anybody not a secret that over the last century, the number of patients with various forms of Allergy has increased several times. Urticaria, angioedema, hay fever, atopic dermatitis and others. Their list can continue. But all of them are one is all the different types of allergies, caused by excessive sensitivity of the immune system. And it is largely the result of the progress of the last hundred years.
At the heart of any allergic process is two groups of reactions. The first contact with the allergen. And only those to which the immune system is particularly sensitive. And the second is the reaction to this contact. It is manifested in the release of special cells of a huge number of substances (bradykinin, histamine, etc.). These substances are actually cause allergic reactions. But other than that they act on cells, causing them to produce the same substance. The result is a cascade of reactions. And he will go as long as all the cells will not stop the production of these substances, called mediators of Allergy.
Since the identification of the mechanisms of Allergy and in these days in medicine is used antihistamines. Now their numbers several dozen and three generations. This is due to the fact that the earlier drugs have enough side effects. And their use in many cases causes people to give up some activities.
Among the drugs of the second generation of the most prominent is the citrine. The medicine has the ability to bind with receptors to histamine for a long time, without exciting them. That is citrine - the cure blocking these receptors and histamine can not realize its effects. Its main advantage, compared with the preparations of the first generation, is the minimal effect on the brain. Thus citrine pills do not cause drowsiness. In addition, the duration is very large - almost 24 hours. Therefore, citrine is taken 1 time per day.
the main indicators of metabolism, citrine is a medication that has a very good characteristics. He has great accessibility. This means that the use of one pill citrine, virtually all medication in an hour, will be in the blood. A large part of proteins associated with blood and slowly released from them. Thereby providing a constant level of concentration. In addition, there is another feature, which has a citrine. The drug is excreted, mostly unchanged, via the kidneys. Only a small part of it is inactivated in the liver. While most other drugs metabolized by the liver.
Citrine is available in tablets, coated. One contains 10 milligrams of citrine and 500 milligrams of excipients. In addition, there is syrup. It is designed for children from two years. This fact is very remarkable, since for many drugs the minimum allowable age of 6 years. And atopic dermatitis affects children at any age. Because children with atopic dermatitis and diathesis shown syrup citrine, medicine, in a convenient form.
When taken in therapeutic doses, 1 tablet 1 time a day, the drug in the blood has a constant concentration. The course is 7-10 days. And the power of actions over time, not decreased, as the citrine does not cause tolerance - gradual decline in sensitivity to the drug. As most other antihistamines. The effect lasts for 3 days after taking the last pill.
Side effects practically no different from all the antihistamines. But usually they are expressed to a lesser degree and often not registered. Among them: nausea, headache, drowsiness.
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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."
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