The so-called Haemostatic or styptic are particularly common in surgical practice. Thanks to such drugs, the doctor can stop the bleeding and save the life of his patient.
Today, among the hemostatic agents are particularly popular such medication, as the ‘Apotex”. Instructions for use, analogs, and side-effects and contraindications of this drug are presented below.
The Drug “Apotex”, the statement of which is contained in the cardboard packaging, sold in the form of a white powder lyophilisate, which is designed for preparation of intravenous solution.
An Active element of this medication is the Aprotinin. As for additional ingredients as they use lactose and sodium hydroxide.
To Acquire the tool can be in bottles of 50 or 10 ml. In one cardboard pack is usually contained 5, 1 or 10 bottles.
What is the drug “Apotex”? Instruction manual says that it is not only hemostatic but antiproteolytic and antifibrinolytic agent.
Consider the drug is able to inactivate proteases plasma of tissues and blood cells, which play a very important role during pathophysiological processes.
The Effectiveness of this tool due to its ability to block the activation of plasminogen and to inactivate the proteolytic effect of plasmin.
Antiprotease action «Protexa” has a positive effect on various lesions of the pancreas. Also, this drug slows down the process of fibrinolysis, lowers fibrinolytic activity of blood and has hemostatic effect in coagulopathy.
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The Ability of a drug to block the kallikrein-kinin system is particularly used in angioedema, as well as in the treatment and prevention of shock.
What are the kinetic characteristics of the drug “Apotex”? Instructions for use reports that after its intravenous administration, he quickly distributed in the extracellular space, and temporarily accumulates in the liver.
Inactivation of the drug occurs in the gastrointestinal tract. The drug is partly destroyed in the liver and kidney. This process is carried out under the action of renal lysosomal enzymes.
Excretion of the active ingredients of the drug occurs within six hours.
In some cases, drug use ‘Apotex”? Instruction manual informs that this drug is particularly effective in:
When it should appoint a lyophilisate “Apotex”? Instruction manual States that contraindications this drug is not very much. It should not be used when:
With caution this medication should be used with cardio-pulmonary shunt operations, deep hypothermia, allergic reactions (in anamnesis), the patient on extracorporeal circulation.
Not to mention the fact that during pregnancy the drug is used only in the second trimester (for health reasons).
If you want to assign the drug during lactation, at the time of his admission, breastfeeding should be discontinued.
Before using the product contents of the vial are dissolved in 2 ml or 20 ml of isotonic sodium chloride solution (depending on dosage).
So how should I use the drug “Apotex”? Instructions description of the drug have reported the following schema:
How should I do an infusion with the drug “Apotex”? Instructions for use (in capsules medicine can be stored for two years) reports that the tool should be administered in the supine position of the patient, a slow intravenous bolus or infusion.
After the introduction of the medication the patient may experience the following adverse events:
Replace medicine can consider using a tool such as “Vero narcap”, “Gordox”, “Aerus”, “Contrical”, “Ingitril”, “Trasilol 500000”, “Incipal”, “Tracklen” and other.
Buy this medication for the price of 450-570 rubles per pack No. 10.
Many patients with chronic pancreatitis report that this medication is very effective. This tool is quite easy way to stop aggravation and normalize the General condition of the patient.
Comparing this solution with ‘Gordeks”, experts point out that “Apotex” more efficient. They also report that this tool is not intended for self-acceptance. Its introduction requires special skills, otherwise the patient may experience numerous unwanted effects.
Article in other languages:
AR: https://tostpost.com/ar/health/7975-mylan-pharms.html
HI: https://tostpost.com/hi/health/7978-apotex.html
JA: https://tostpost.com/ja/health/7977-apotex.html
PL: https://tostpost.com/pl/zdrowie/14214-lek-aproteks-instrukcje-stosowania-opis-opinie.html
TR: https://tostpost.com/tr/sa-l-k/14223-la-aproteks-kullan-m-talimat-a-klama-yorum.html
Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."
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