Steatosis of the liver – this is a disease that is manifested by degeneration of the tissue (parenchyma) of the liver no cellular reaction. In its origin and course of the disease is acute or chronic. Steatosis of the liver with chronic, sometimes cholestatic and fatty.
The Acute form of liver develops when exposure to toxic substances and poisoning of various origins. It could be a poisoning by alcohol surrogates, heavy metals, phosphorus, medicines, poisonous plants, mushrooms etc. This form of the disease is also called yellow atrophy of the liver. In rare cases, acute steatosis of the liver develops as a result of existing hepatitis or sepsis infectious etiology.
The name of the disease suggests that it has an acute onset. First observed the phenomenon of dyspepsia (nausea, vomiting) and signs of intoxication. The patient feels “fatigue”, body aches, muscle pain, complains of increasing the temperature. Later jaundice. Liver slightly increased in size, then its size is reduced and it is not palpable. Increases the content of liver enzymes (ALT, AST), blood glucose. Histological examination of the tissues of the body, marked fatty degeneration. Severe disease can be combined with liver failure with the transition into a coma, blood clotting and increased bleeding.
Patients with acute hepatosis subject to compulsory hospitalization. The success of further treatment depends on how quickly treatment is started and stopped the flow of toxins to the liver. To do this, perform lavage of the stomach and intestines. With bleeding transfusions of fresh frozen plasma, albumin, optionally erythrocyte mass. Conducted infusion therapy glucose solution, salt solutions with added potassium, b vitamins, and folic acid. In severe cases, may need plasmapheresis and hemodialysis.
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Chronic steatosis the liver appears fatty degeneration of the liver cells. This form of the disease has a prolonged course and alternates with periods of exacerbation and relative decline of the disease. Cause of fatty degeneration is essentially chronic alcoholism. In rare cases it occurs on the background of prolonged exposure to hepatotoxic substances in the workplace. Associated severe diseases, such as diabetes or metabolic disorders may also cause steatosis. The symptoms of disease develop permanent weakness, aching pain in region of liver. The body may be slightly enlarged, on palpation, tenderness. The spleen is not increased. Jaundice usually does not happen or there is a slight ikterichnost skin and sclera. In the blood is moderately increased liver enzymes and cholesterol.
When terminating the toxic effects on the body, avoiding alcohol possible full recovery. In the diet of the patient should prevail proteins. Limit the intake of fats. Assigned hepatoprotectors and multivitamins.
The Next sort of chronic form of the disease is cholestatic hepatosis liver. Its symptoms are expressed by the delay of hepatic bile and accumulation of pigment in liver cells. The hepatocytes are exposed to protein malnutrition. This disease develops as a result of toxic exposure to chemicals and medicines. This leads to metabolic disorders in the liver education is broken and the normal flow of bile.
The Disease manifested severe jaundice, lightening of stool and dark urine. The liver is usually increased in size. In the blood increased content of bilirubin, enzymes, phosphatase and cholesterol. The treatment of this form of steatosis is about the same as in the fatty form, except that in the treatment applied corticosteroids.
The Prevention of all forms of hepatosis is proper nutrition, the rejection of the systematic use of alcohol, occupational health, especially in hazardous work, and, of course, a systematic medical examination in high-risk groups.
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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."
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