Tablets "Equator" represents the combined antihypertensive agents, the use of which contributes to a reduction in arterial pressure, total vascular resistance and preload. The basis of this drug is reduced concentration of aldosterone and angiotensin II in plasma, as well as the improvement of the vasodilator bradykinin. In addition, this combination means prevents the flow of calcium ions into vascular smooth muscle cells and myocardium by inhibiting the so-called calcium channels. The decrease postnagruzki on the heart and the expansion of the arterioles and arteries of the peripheral type, similarly provides the drug "Equator". Tablets, the price of which averages 450 rubles, also have a pronounced antianginal effect.
With regard to the composition of the antihypertensive agents, the active (active) components it contains dihydrate of lisinopril and amlodipine besylate. as additional substances are sodium starch glikolat, magnesium stearate, microcrystalline cellulose 101 and 12.
The Main indication for the appointment of such combination drug tablets like the Equator, is essential hypertension. As contraindications are angioedema, angioedema or hereditary idiopaticescoe type, cardiogenic shock, myocardial infarction, allergic reaction to besilate amlodipine or lisinopril dihydrate. In addition, it is not necessary to use this antihypertensive agent in arterial hypotension, hemodynamically significant aortic stenosis or mitral valve, unstable angina, heart failure and hypertrophic cardiomyopathy. Blood pressure pills "Equator" is not recommended and pediatric patients, pregnant and lactating mothers.
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With great care used it with azotemia, ischemic heart disease, bradycardia, coronary insufficiency, tachycardia, cerebrovascular disease, mitral stenosis, primary hyperaldosteronism, hyperkalemia, aortic stenosis, disorders in the kidney and liver, diabetes and lupus erythematosus.
We should also tell about the possible adverse reactions associated with the use of this combination drug. So, for example, tablets Equator can cause headaches, weakness, drowsiness, dizziness, nausea, diarrhea, dry cough and vomiting. In addition, there may be agranulocytosis, orthostatic hypotension, sleep disturbances, angioedema of the face, hyperglycaemia, mood changes, bronchospasm, visual disturbances, dyspnea, rhinitis, gynecomastia, allergic alveolitis, tinnitus and nocturia. Arthralgia, skin rashes, itching, Raynaud's phenomenon, tremor, myalgia, fatigue, paresthesia, asthenia, neuralgia and hyperesthesia can also be triggered by therapy, the main place in which take the pills "Equator".
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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."
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