Gamma-aminobutyric acid. Signs of deficiency in the body

The Main controller of our body – the brain. Thanks to him koordiniruyutsya of operation of all systems. With the help of the brain and spinal cord we can move, see, hear, speak, feel and understand. Naturally, the Central and peripheral nervous system exert their effect through special structures – neurotransmitters. These include a number of substances which help the brain in transmitting signals.

The Action of neurotransmitters in the body

To realize the communication between nerve fibers and muscle tissue, necessary assistants. They are the intermediaries that conduct the electrical impulse across the synaptic space. Impulses are transmitted along the nerve ending and reaching the end, cause the release of neurotransmitter. “Helpers” enter the gap and affect neighboring neuron, which becomes permeable for the signal. Thus, by the transmission of electrical impulses in the body. Neurotransmitters – are substances of chemical origin that can cause both excitation and inhibition in the Central nervous system. They are divided into 3 groups: amino acids, catecholamines, and peptides. The most common representatives are epinephrine and norepinephrine, gamma-aminobutyric acid, glycine, dopamine, serotonin, glutamate, acetylcholine.

Functions of GABA in the body

Gamma-aminobutyric acid (GABA English) refers to the mediators that inhibit the nervous system. It is a chemical substance that is present in humans and animals. GABA refers to the number of amino acids that are not capable of synthesizing protein molecules. Despite this, its importance in the body is very large. Gamma-aminobutyric acid performs 2 important functions:

1. Mediator action. Due to its braking effect, GABA has hypotensive, sedative, anticonvulsant effects. In addition, it helps to stimulate sleep, regulates motor activity, improves the processes of memory and thinking.
2. Metabolic function. GABA improves the metabolic processes in the brain and its circulation, provides nerve cells with energy. Thanks to this substance is one of the most important effects – antihypoxic, that is, the prevention of oxygen starvation. Following the action of GABA – removal from the body products of metabolism and the impact on the stimulation of production of growth hormone by the anterior lobe of the pituitary gland.

Sources of gamma-aminobutyric acid

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GABA is one of the components of blood and brain tissue. The shortage of natural reserves must receive it from other sources. Gamma-aminobutyric acid present in some plant foods. These include tea leaves and coffee, filamentous fungi, and also the juice of plants of the genus Cruciferae. In addition, GABA is produced by chemical means using microbiological techniques. To develop use of the bacteria, for example E. coli. Some medicines contains basic stuff – nicotinoyl gamma-aminobutyric acid. It relates to peers received by the laboratory.

Signs of deficiency of GABA in the body

With a lack of gamma-aminobutyric acid, a number of pathological processes. The main ones – depression, anxiety, and cramps in the muscles. It is associated with reduced functions in the body, gamma-aminobutyric acid. GABA is needed to provide the brain with energy, control the processes occurring in it. Therefore, when its shortage is developing many disorders of the CNS. These include:

1. Vascular pathology of the brain – hypertension, atherosclerosis, development of strokes and heart attacks.
2. Headache, weakness, dizziness, sleep disturbance, memory and attention.
3. Epilepsy.
4. Alzheimer's Disease.
5. Cerebral palsy.
6. Encephalopathy.
7. Increasing the level of growth hormone.
8. Dementia after brain injury.
9. Parkinson's Disease.
10. Depression.
11. The Underdevelopment of the mental processes of children.
12. Unstable mental status.
13. Sea and air sickness.

All these conditions require medication and replenishment of gamma-aminobutyric acid and increased consumption of products which it contains.

Medicines containing GABA

In order to compensate for a lack of gamma-aminobutyric acid, it is necessary to consult a doctor. He will prescribe adequate replacement treatment. The main ingredient of all drugs – gamma-aminobutyric acid. The analogues contain additives in the form of calcium, nicotinoyl and are derivatives of GABA. Essential medicines are medicines “Aminalon”, “Pikamilon”, “Phenibut”, “Narbutas”, “GABA”. Indications for the use of all these drugs are disorders caused by a deficiency of gamma-aminobutyric acid in the body. Medicines containing GABA,contraindicated in children under 1 year, pregnant women (first trimester), if you are sensitive to the main or auxiliary substances and acute renal failure.

Gamma-aminobutyric acid: patient testimonials

The appointment of GABA or its analogues in patients with significantly increased efficiency, regulation of sleep and wakefulness, improved memory and reduced depression, relieved seizures. Among the side effects some patients report dyspepsia, increased libido, drowsiness.