Statins - what is it? Statins (drugs): name

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2018-03-18 09:40:52

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statins what is this

Statins-drugs that can be prescribed exclusively by a doctor and only after a series of blood tests that determine cholesterol levels. In such cases, their main goal – protecting the cardiovascular system from diseases and acquired pathologies. When prescribing doctor is obliged to advise the patient on the following items:

  • Statins - what is it;
  • Complex side effects from the medication.

The physician holds a conversation on the topic that statins need to be taken continuously. Only under this condition they do protect the heart and blood vessels and have a pronounced therapeutic effect.

The Concept of cholesterol

Cholesterol-is a lipid with natural environment: 80% is synthesized in the liver and 20 enters the body with food. The role of cholesterol in the proper functioning of the body is quite important: it is one of the building materials at the cellular level, activates metabolism, protects cells from the effects of negative factors involved in the development of bile acids and sex hormones. Cholesterol is “good” and “bad”. But from a medical point of view, this classification looks as follows:

  • HDL-high-density lipoproteins. People with high content of cholesterol in the blood not susceptible to heart diseases. The excess HDL is transported back to the liver, where it undergoes a synthesis, therefore, is not going to cholesterol plaques, and does not pose a threat to health. In this case, the intake of statins is not needed, because the body is running smoothly and harmoniously.
  • LDL-low density lipoproteins. The main danger for the body they are, when they unite in cholesterol plaques. The danger of this
    Phenomenon? Atherosclerotic deposits, which are deposited inside the blood vessels (on the walls), clog them, thereby disrupting the blood flow. This leads to oxygen deficiency, strokes, heart attacks.

statin drugs

Statins – what is it?

In the twentieth century, atherosclerosis has been recognized as one of the leading causes of death, because he is the cause of myocardial infarction and stroke. For a long time the erroneous was the opinion of doctors that atherosclerosis – it is an irreversible and natural process of aging. The discovery of statins has been a revolution in the world of medicine: they had a powerful cholesterinspiegel property. The results of the study, which was conducted over 5 years, were the following indicators:

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  • Lower levels of LDL (bad cholesterol) by 35%.
  • Increase levels of HDL (good cholesterol) by 8%.
  • A Reduction in strokes by 30% and myocardial infarction by 42%.

Statins-medications that promote and regulate the synthesis of cholesterol in the body, reduce its concentration by inhibition of HMG-COA reductase.

Who are prescribed a statin

According to studies, after taking drugs was noted positive dynamics in patients with chronic ischemic heart disease. Evidence that the positive effects of statins with other pathology and diseases exist, there is no. But these tools are not only curative but also preventive. As statins-drugs that reduce cholesterol, they appoint the people belonging to such categories:

  • Persons with homozygous familial hypercholesterolemia, which is not amenable to treatment with gipolipidemicheskih medicines.
  • Patients suffering from coronary heart disease, regardless of cholesterol level.
  • Patients who have had a heart attack and angina sufferers.
  • Patients with coronary syndrome.
  • Diabetics to adjust the level of cholesterol in the blood.
  • Patients suffering from hypertension related to risk for cardiovascular disease.
  • Patients suffering from atherosclerotic lesions of blood vessels. These conditions include atherosclerosis of cerebral vessels, lower extremities, renal arteries, and the presence of atherosclerotic plaques in the carotid artery.
  • Persons suffering with heart disease but with high levels of cholesterol in the blood.

statin medication

Statins-medications that are among the best prevention tools in the fight against cardiovascular diseases. According to statistics, in countries where increasing the level of sales of these drugs, the mortality rate from diseases associated with high levels of cholesterol in the blood is greatly reduced.

«For» and «against»

So, statins. What is it and how much they needed – we have considered above. But the opinion of doctors about these drugs is ambiguous. There is good “” and “against” regarding these medicines. Despite the fact that advertising slogans promise to spare people from atherosclerosis and all of the ensuing disease, statins are not always and not in any measure useful. Especially controversial is the question of their acceptance by older people: first, statins-the drugs, the price of which is suitable for all; secondly, side effects can cause more harm than good when you receive drugs as a preventive medicine. Based on the results of clinical trials conducted by different institutions, experts say

  • statins-name drugsThe Use of statins as a preventive means of reducing the risk of heart attack or stroke, really high, but the side effects make doctors to think before you assign them to patients previously not faced with heart disease.
  • Especially carefully prescribe statins to people who have symptoms of cataracts or have already suffering from this disease. According to statistics, the medication increases the risk of cataract development by 52%.
  • This applies to older people with diabetes. The taking statins provokes the development of cataracts in 5.6 times faster.

But, nevertheless, the newest statins are used in medical practice more often and bring their favor. An experienced physician must advise the patient before the treatment using these drugs on such issues:

  • Statins – what is it?
  • What to expect from the medication: the positive side of treatment and prevention.
  • Side effects and effects of taking the drug.
  • How and in what doses to take drug.

Statins and cholesterol: the flip side

Drug-induced reduction of cholesterol in the blood involves a change in the other indicators in the body:

  • Statins reduce the production of not only cholesterol, but also his predecessor – mevalonate. He is the source of many important substances that perform biological functions in the body. Lack of these substances can cause other diseases.
  • Low cholesterol can be more harmful than high: this leads to increased risk of cancer, anemia, diseases of the nervous system and liver.
  • According to research conducted in USA, increased levels of cholesterol triggered by low magnesium content in the body. Its deficiency leads to of angina, hypertension, diabetes and arrhythmias.
  • The"Bad" cholesterol is actively involved in tissue repair at the cellular level. The taking statins may inhibit this function, leading to myalgia (weakness, edema, muscle pain) and even muscular dystrophy.

Side effects

The dangers of statins during their chronic administration is expressed with such side effects:

  • Allergic reactions: itching, skin rash, urticaria, anaphylaxis, exudative erythema, Lyell's syndrome.
  • Digestive system: stomach upset, nausea, vomiting, hepatitis, pancreatitis, jaundice.
  • The Organs of hematopoiesis: thrombocytopenia.
  • Nervous system: dizziness, paresthesia, amnesia, peripheral neuropathy, malaise and weakness.
  • Musculoskeletal system: cramps, back pain, arthritis, music.
  • Metabolism: hypoglycemia (lower blood sugar), the risk of diabetes.

Long-term use of statins can lead to insomnia, headaches, impotence, weight gain or anorexia.

Some principles of selection of statins

If, after all “for” and “against” the decision was made to prescribe a statin, it is necessary to consider some features: compatibility with other drugs and presence of chronic diseases.

  • statin drugs priceTaking statins with drugs for gout, diabetes and hypertension can cause the risk of myopathy doubled.
  • In chronic liver diseases need to take drugs with additional protective functions. This rosuvastatin at low doses and pravastatin (“Pravachol”). Together with them is strictly prohibited to take antibiotics and alcohol.
  • Regular muscle aches and pains or physical stress that can cause damage to muscle tissue, advisable to take pravastatin.
  • With special ostorojno...

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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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