The Drug is "Lekamen" is relatively new. According to the instructions of the manufacturer, the drug does not cause characteristic medications of its group side effect-swelling in the legs.
The Drug is a blocker of slow calcium channels, refers to a derivative digidropiridinovmi series. The medication helps slow the transmembrane current of calcium into the smooth muscle cells and cardiomyocytes. Characterizing the hypotensive effect of the drug Lekamen", the instruction for use indicates the ability of tools to influence directly relaxing the smooth muscles of blood vessels, reducing their total peripheral (vascular) resistance. The drug has a prolonged (long) antihypertensive effect. High selective ability of the drug eliminates the development of negative inotropic effect (change in the amplitude of contraction of the heart).
Means "Lekamen" instructions for use recommends with moderate and mild essential hypertension.
The Drug is designed for oral administration (oral).
Generally, the recommended dosage is 10 mg (the drug "Lekamen 10"). The tablets should be taken before meals in fifteen minutes, preferably in the morning. In accordance with the received therapeutic result, the dosage can be increased to 20 mg.
Optimally effective quantity of the drug "Lekamen" instruction manual recommends to pick up gradually. Dosage increase (if necessary) to 20 mg produced no earlier than two weeks after starting the medication.
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Swallow the Tablet whole with water in sufficient volume.
The side effects of the drug "Lekamen" instructions for use include the effects due to the vasodilating action, as well as diarrhea, pain in the epigastrium, dyspepsia, myalgia, drowsiness and others. It should be noted that these negative reactions are rare and usually reversible. Drug "Lekamen" (feedback of patients and physicians testify to this) is transferred well enough.
The drug is Contraindicated in chronic heart failure decompensation, in aortic stenosis, unstable angina, disorders of the liver and kidney Express. Medicine "Lekamen" is not assigned with lactose intolerance, after suffering a heart attack (during the month), with galactosemia, children under the age of eighteen. The drug is contraindicated in pregnancy, lactation, malabsorption syndrome and galactose or glucose. Not prescribed to women in reproductive age not using reliable contraception, with hypersensitivity to components of drug or other derivative digidropiridinovmi group.
Overdoses in clinical practice have not been recorded. Presumably when taking high doses of the drug "Lekamen" may be peripheral vasodilation (vasodilation) reflex tachycardia and hypotension, myocardial infarction, increased frequency and duration of angina attacks.
For relief of the condition, symptomatic therapy.
Drug interactions.
As shown by clinical practice, the drug "Lekamen" in combined therapy of working quite well with diuretics, beta-blockers and some other means. Caution should be observed when administered in conjunction with drugs, "Erythromycin", "Intrakonazol", "Ketoconazole".
When drinking grapefruit juice is probably the antihypertensive properties of the medication "Lekamen".
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Alin Trodden - author of the article, editor
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