What is creatinine? The norm of creatinine in the blood. What are the dangers of high or low creatinine levels in the blood

One of the most important indicators in a laboratory study of blood is creatinine. What is creatinine? This is the final product of breakdown of proteins actively involved in energy processes of the muscle and other tissues of the body.

General information

The Synthesis of creatinine occurs in the liver, it enters the bloodstream, then the kidneys and excreted with urine. During their normal operation, it should not accumulate in the body.

The Norm of creatinine in the blood of various men, women and children, since the quantity of this substance is dependent on the muscle mass of the human body, age, gender. Under the influence of pathological and physiological factors, changes of its concentration, the increase of which – it is a signal of malfunctions in the body.

Signs of increased natural metabolite

What is the creatinine? It is a derivative of creatine, needed for energy production in muscles. Symptoms indicating the need for research of blood:

• Fatigue;
• Shared persistent weakness;
• Swelling of the legs;
• Pale skin;
• Muscle pain;
• Reducing the amount of urine passed.

Pathology, in which creatinine above normal

Increased creatinine in the blood - what is it? This figure increases in unsupervised sports. And when you perform physical exercises contribute to building muscle, large consumption of protein foods and taking certain medicines (antibiotics, cephalosporins). In addition, increased substance due to pathologies associated with metabolism in the body:

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• Radiation sickness;
• Dehydration;
• Various diseases of the endocrine system;
• Renal failure;
• Mechanical damage to the muscle or damage associated with surgical interventions.

On the same line we can talk only in cases of excess creatinine in the blood from the norm.

The Disease, which doctors diagnose based on the results of biochemical analysis:

1. Oncology. Metastasis and malignancy are destroying muscle tissue. There are forms of cancer where significant changes in the liver and kidneys, which inevitably leads to increase in creatinine.
2. Injury muscle tissue. Of the damaged muscles with extensive lesions is the release of natural metabolite. This figure comes back to normal when healing.
3. Disorders associated with the endocrine system. Excessive secretion of hormonal substances destroys muscle tissue, and as a result, creatinine level increases. The danger lies in the fact that for a long time the disease is asymptomatic.
4. Violations of functions of kidneys. Under certain conditions the body does not cope with its function, harmful substances remain in the blood and not excreted in urine. At critical the doctor assigns to the patient a dialysis session.
5. Heart failure. Heart muscle cells are destroyed and contribute to the release of creatinine, as a result, it increases in the bloodstream.
6. Nephrectomy. When one kidney is removed, the second takes over the entire load and, therefore, the indicators can be improved.

Physiological reasons for high level of natural metabolite

The reasons for the increase in creatinine in some situations are not pathological. This is a condition in which muscle mass increases body:

• Reinforced sports. The amount can be on the upper tolerance or above.
• When changing lifestyle to more active and agile.
• When taking certain medications: antibiotics tetracycline, nonsteroidal anti-inflammatory drugs and others. As a result of biochemical reactions creatinine is formed and enters the blood.
• Eating large amounts of meat also contributes to the excessive intake of this substance in the blood.

Clearance

What is the creatinine? This substance, which is produced as a result of biochemical reactions in muscle tissue.

To identify the reasons for its increase in calculated glomerular filtration rate using special formula, which takes into account the age and weight of the person. The figure so calculated creatinine clearance. If it is low, it is associated with the presence of disease, namely renal failure.

Recommended diet

Low excess contents of creatinine from acceptable norms it is possible to adjust the diet:

• Drink a day not less than eight glasses of water. Dehydration increases this index in the blood. In addition, a lack of body fluids leads to a decrease in volume of allocated urine, which also increases the substance. On the other hand, excess water adversely affects the kidneys, they can not cope. Excessive fluid intake can cause an increase in blood pressure, which increases the load on the kidneys. Correct drinking regime will help to correct your doctor.
• Intake of protein foods should not exceed 250 grams per day.
• Fatty foods of animal origin should be abandoned. Give preference to vegetable proteins is necessary.
• Limiting the intake of salt. The average number per day should not exceed three grams, its content in food retains fluid in the body increases the pressure and thus increases the concentration of the natural metabolite.
• Foods high in phosphorus content have a negative influence on this indicator and make the job of kidneys. It is recommended to limit intake of: zucchini, pumpkin, cheese, nuts, soy and low-fat dairy products.
• To Minimize the consumption of potassium. Trace element accumulates in the body, and unhealthy kidneys are not doing its excretion in the required quantities.

Ways to reduce creatinine

1. In addition to the diet you should reduce physical activity. Physical education contribute to a more rapid conversion of ingested food into energy. As a result, more creatinine is formed, and its concentration in the blood increases. However, moderate exercise is essential for health. In this case, it is important to find a balance. For example, instead of basketball – doing yoga or walking.
2. Full sleep at least 8 hours, definitely has a positive effect on the kidneys. If people are constantly not getting enough sleep, the body experiences stress, which provokes more active work of muscles in a typical load or without it. This condition, in turn, affects the kidneys, which starts well enough to filter this product.
3. Monitoring of blood pressure values and, if necessary, regular intake of medications.
4. In the case of existing diabetes requires constant medical therapy, as this disease is one cause of renal disease, and accordingly, high creatinine level.
5. If necessary, the doctor appoints drugs, or dietary supplements, promoting the normalization of the concentration of creatinine in the blood.
6. Laser therapy improves the functioning of the kidneys, and they filter out more intense and the withdrawal of the decay products.
7. Massages relieve stress, improve blood circulation, relax the whole body and convulsions.

Causes of low concentration natural metabolite

Lower content of creatinine in blood - what is it? Meet a condition in which the level of this substance is reduced:

• Fasting for a long time;
• Vegetarianism;
• Not drinking enough protein foods;
• Atrophy of the muscles that occurs when stationary or sedentary lifestyle;
• The hormonal drugs: corticosteroids.

In certain life periods in the female half of the population there is a physiological decrease in the concentration of creatinine in the first and second trimesters of pregnancy. The third indicator is normalized.

How to treat increased creatinine?

Hold the events directed on elimination of the reasons. The patient intravenous drugs - sorbents and diuretics, which increase urine output and helping the kidneys remove this substance. Such manipulation is effective when the normal operation of the urinary system and the blood flow exogenous or endogenous creatinine. When renal failure is prescribed hemodialysis. In this case, the blood is cleaned using a special device called "artificial kidney" in stationary conditions. Carry out this procedure three times a week.

Traditional medicine also offers several ways to reduce creatinine. The use of medicinal herbs is possible under condition of normal renal function. Brewed teas from herbs that have a diuretic effect: the leaves of sage and nettle; dandelion roots. The daily intake of the drink activates the kidneys and stimulates the increased separation of urine, respectively, and creatinine. Before proceeding to its reduction, should consult a doctor to determine the tactics of treatment.

Alternative methods

The End product of metabolism in muscle tissue ...