The interaction of nonallelic genes: types and forms

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2018-03-28 08:59:15

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The Transfer of characteristics from generation to generation due to the interaction between different genes. What is a gene and what are the types of interaction between them?

What is a gene?

The genome currently mean the unit of transmission of genetic information. Genes are in DNA and form structural sections. Each gene is responsible for the synthesis of a certain protein molecule, which causes the manifestation of a characteristic of a person.the interaction of nonallelic genes

Each gene has several subtypes or alleles, which cause a variety of signs (for example, brown eye color is caused by a dominant allele of the gene, while blue color is a recessive trait). Alleles are located in identical parts of homologous chromosomes and the transmission of a particular chromosome leads to the expression of a particular characteristic.

All genes interact with each other. There are several types of their interaction-allelic and nonallelic. Accordingly, we distinguish the interaction between allelic and nonallelic genes. How do they differ and what impact?

History

Before it was opened types of interaction between nonallelic genes, it was assumed that the only possible complete dominance (if there is a dominant gene, the trait will manifest itself; if it does not, then the trait is). Dominated by the doctrine of allelic interaction which has long been the basic dogma of genetics. Dominance has been thoroughly researched and were open to such types as complete and incomplete dominance, codominance, and serdolikovaya.types of interaction between nonallelic genes

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All these principles obey the first law of Mendel, which read about the uniformity of first generation hybrids.

For further observation and study it has been observed that not all the signs were adjusted to the theory of dominance. At a deeper study it was proved that not only the same genes affect the expression of the characteristic or group of characteristics. Thus was opened the form of interaction between nonallelic genes.

Reactions between genes

As has been said, for a long time dominated by the doctrine of dominant inheritance. In this case, was the place of allelic interaction in which the symptom appeared only in the heterozygous condition. After it was open to various forms of interaction of nonallelic genes, scientists were able to explain hitherto unexplained types of inheritance and to get answers to many questions.forms of interaction of nonallelic genes

It Was found that gene regulation is directly dependent on enzymes. These enzymes allow the genes to react differently. The interaction between allelic and nonallelic genes proceeded by the same principles and schemes. This allowed us to conclude that inheritance does not depend on the environment in which genes interact, and the cause of atypical transmission characteristics lies in the genes.

Nonallelic interaction is unique, allowing you to get a new combination of characteristics that lead to a new degree of survival and development of organisms.

Nonallelic genes

interaction between allelic and nonallelic genes

Are those Nonallelic genes that are localized in different parts of the homologous chromosomes. Function is synthesis they have one, however they encode for the formation of various proteins, causing different symptoms. These genes react with each other, can result in the development of signs in several combinations:

  • Another sign is due to the interaction of several, quite different in structure genes.
  • Several signs will depend on a single gene.

Reactions between these genes there are several more complicated than for allelic interaction. However, each of these types of reactions has its own features and characteristics.

What are the different types of interaction between nonallelic genes?

  • Epistasis.
  • Polygenic.
  • Complementarity.
  • Action modificatory genes.
  • Pleiotropic interactions.

Each of these types of interaction has its own unique properties and manifested in different ways.

You Should go into more detail on each of them.

Epistasis

The interaction of nonallelic genes-epistasis-are observed in the case when one gene suppresses the activity of the other (the inhibitory gene is called epilating, and the suppressed – is hypostatic gene).

The Reaction between these genes can be dominant and recessive. Dominant epistasis is observed in the case when the epistatic gene (usually designated by the letter I, if it has external, phenotypic expression) suppresses the hypostatic gene (it is commonly referred to In a or b). Recessive epistasis occurs when the recessive allele of the epistatic gene suppresses the manifestation of any of the alleles of the gene gemostaticescoe.the interaction of nonallelic genes epistasis

The Splitting to the phenotypic trait, each of these interactions is also different. When dominant epistasis is more common following picture: in the second generation the phenotypes of the separation will bethe following – 13:3, 7:6:3 or 12:3:1. It all depends on what genes will converge.

When recessive the epistasis sharing such: 9:3:4, 9:7, 13:3.

Complementary

The Interaction of nonallelic genes in which when you combine the dominant alleles of several signs of a new, hitherto not seen in the phenotype, is called complementarity.

For Example, most often this type of reaction occurs between genes in plants (especially pumpkins).

If the genotype of a plant has a dominant allele A or b, the vegetable gets a spherical shape. If the genotype recessively, the shape of the fruit is usually elongated.

The presence in the genotype of two dominant alleles (A and b), the pumpkin becomes discoid in shape. If you continue to hold the crossing (i.e., to continue this interaction of nonallelic genes with pumpkins clean lines), the second generation of can to 9 individuals with a discoid shape, 6 – with a spherical and one elongated pumpkin.

This crossing provides a new, hybrid forms of plants with unique properties.

This type of interaction causes the normal development of hearing (one gene – the development of the snails, the other – the auditory nerve), and in the presence of only one dominant trait manifested by deafness.

Polygenic

Often the basis of a trait is not the presence of dominant or recessive alleles of a gene, and their number. The interaction of nonallelic genes-polygenic-is an example of such manifestations.

Plastic action of genes can occur with cumulative (cumulative) effect or without it. When the accumulation degree of a trait depends on the General genetic interactions (the more genes, the stronger the trait is expressed). The offspring, when such effect is divided in the following way – 1:4:6:4:1 (the severity of the symptom decreases, ie, one individual sign the most pronounced, others observed his demise up to complete disappearance).

If cumulative effects are not observed, the manifestation of the trait depends on a dominant allele. If there is at least one such allele, a sign will take place. With such a splitting effect in the offspring occurs in the ratio of 15:1.

The Action of genes-modifiers

The Interaction of nonallelic genes, which is controlled by the action of modifiers, occurs relatively rarely. An example of such interaction is as follows:

  • For Example, a D gene that is responsible for color intensity. In dominant state, this gene regulates the coloration, while in the formation recessive genotype for this gene, even if there are other genes that control directly the color will be revealed "effect of the dilution of color”, which is often observed in mice and milky-white.types of interaction of nonallelic genes
  • Another example of such a reaction is the appearance of spots on the body of animals. For example, a gene F, the main function of which – the uniformity of dyeing wool. During the formation of the recessive genotype wool will be dyed unevenly, with the advent of, for example, white spots in a particular area of the body.

This interaction of nonallelic genes in humans is pretty rare.

Pleiotropy

In this type of interaction one gene regulates the expression of or affects the severity of another gene.

Animals pleiotropy is manifested as follows:

  • Mice example of pleiotropism is dwarfism. It has been noticed that by crossing phenotypically normal mice in the first generation all mice were dwarf. It was concluded that the dwarfism is caused by a recessive gene. Recessive homozygotes continued to grow, showed the immaturity of their internal organs and glands. This gene of dwarfism affecting the development of the pituitary gland in mice, and led to a decrease in the synthesis of hormones and caused all the consequences.
  • A platinum color in foxes. Pleiotropy in this case manifested a lethal gene, which in the formation of dominant homozygotes caused embryos death.
  • People Have a pleiotropic interaction is shown by the example of phenylketonuria, as well as Marfan syndrome.

The Role of nonallelic interaction

In evolutionary terms, all the above types of interaction of nonallelic genes play an important role. New gene combinations lead to the emergence of new characteristics and properties of living organisms. In some cases, these signs contribute to the survival of the organism, in other – on the contrary, cause the death of those individuals that will significantly stand out among its kind.complementarity of the interaction of nonallelic genes

Nonallelic interaction of genes widely used in wheat breeding genetics. Some species persist through a similar gene recombination. Other types of purchase properties which are highly valued in the modern world (e.g., new breed animals with greater stamina and physical strength, than her parent).

Work is Underway on the use of these types of inheritance in humans with the aim of eliminating negative signs from the human genome and the creation of a new, defect-free genotype.


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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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