ASAT and Alat are the norm for adults and children

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2018-03-28 09:16:08

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Alat (full name – alanine aminotransferase) - an enzyme produced in the liver and involved in the metabolism of amino acids. If the rate of Alat in the blood is exceeded, this may be the first sign of any disease. Enzyme in a serious amount is in liver, skeletal muscle, kidney and heart muscle. Much less in blood serum, for normal Alt in the blood presents a negligible amount of this substance. Exceeding it may be the first sign of any pathology, but not always.

If the cell bodies, which contains this substance, for some reason begin to collapse, then the blood in large quantities enters the Alat. The norm in the serum – from about 0.1 to 0.68 µmol/ml h, Or about 30-40 units per liter. That is, in a healthy human body in very small amounts is present in Alat. The norm for women up to 31 units per liter for men – up to 41 units in one liter. The increase in Alt can cause diseases such as hepatitis, toxic liver damage or liver cancer, cirrhosis, alcoholism, heart disease – heart attack or heart failure, the withering away of skeletal muscles. After serious shock or burns may increase Alt. The norm is often exceeded in large infarcts. And a very serious increase occurs during the incubation period of infectious hepatitis.

ASAT (the full title – glutamate oxaloacetate transaminase or aspartate aminotransferase) - an enzyme which has the highest concentration in the myocardium, liver, kidney and skeletal muscle. This enzyme is more active in the body for men than women. If the activity of AST in the blood is increased, it may indicate damage to the cells of the body, at least – about the dysfunction of this body. If there is damage to the heart muscle, in this case, there is the greatest surge of activity of ASAT-activity it may increase to 20 times. The more the focus of necrosis in the myocardium, the greater the content of the enzyme in the blood. The norm of Alat in the blood of children much lower on average than adults. In the blood of girls aged 7 to 12 years this norm corresponds to 13-21 unit, and in boys of the same age, this strap as the top and bottom, may be higher on average by 4 points. Adolescents have a norm of Alat in the blood may be lower than in children younger. So, girls aged 13 to 17 years, the norm ranges from 10 to 13 units per liter, the boys in the same age category – from 10 to 15. This is the average for adolescents of the indicator Alt. The norm for older men not changing, and older women & ndash; is reduced by 2-3 units in one liter.

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And Alt, and AST are enzymes – aminotransferase. These enzymes are most active in the entire body of any person. Most of Alat in the liver, and AST – in the tissues of the muscles, especially the – in the tissues of the myocardium, heart muscle. ASAT consists of a cytoplasmic and a mitochondrial isozyme of the isozyme. 80% of the total activity of AST is accounted for by the cytoplasmic isoenzyme. In the serum of two of these isoenzymes is usually determined only cytoplasmic.

Norm AST, Alt exceeded in various lesions of the liver. In particular, damage alcoholic, drug or toxic, cirrhosis, hepatitis, etc. If there is a toxic poisoning of the liver due to the intake of certain medications, in this case the norm of ASAT, Alat exceeded. Any toxic effect on the liver can lead to such a result. Norm AST, Alt increases due to factors that have nothing to do with malfunctions in the liver. These factors include infant age – up to six months (increase in the level of these enzymes in babies is normal), tissue damage of the heart muscle, heat stroke, the course of the disease of TBSA in children, inflammation of muscles, hemophilia, obesity and many others.

Norm AST, Alt, in the body is sometimes underestimated. This happens because of renal failure, deficiency of pyridoxine, i.e. vitamin B. It also may be the result of a repeated hemodialysis procedure. It may well be absolutely normal that the pregnant woman's body lowered (raised) ASAT or Alat. The norm in pregnancy is often violated due to the fact that in the body of the mother undergoes a systemic restructuring.


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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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