Sodium thiosulfate: not only the antidote

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2018-03-28 21:22:08

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This drug is administered to the patient intravenously. Primarily sodium thiosulfate – it is a cyanide antagonist. That is, in cases of poisoning by cyanides by using this medication man can be saved. According to the classification of this substance for immediate assistance. In practice, there are still some indications for its use, read more in this article.

As you know, when the cancer chemotherapy patient dealing with a large number of toxic substances that are usually very poorly tolerated by the majority. And sodium thiosulfate can reduce the side effects one of the substances in this class – cisplatin. It is clear that in this case, without the doctor's recommendations one this drug does not apply.

As with many other drugs, to thiosulfate true rule: use only if benefit more than harm. That consider the doctor when prescribing the drug “Sodium thiosulfate”? Instruction manual recommends that you consider the following factors.

  • Allergic reactions: if ever you were allergic to citrus, you still need to tell the doctor. And certainly it should be done, if you remember drug allergies. Of course, it will be the doctor;
  • Young age: although there was no experimental data about the effect on children, doctors try not to prescribe sodium thiosulfate to children. Of course, if you need to save from poisoning, all means are good. Including this;
  • Old age: experimental data either, but it is assumed that there is a big difference in side effects between young and elderly patients. So often age does not become a reason for refusal the purpose of the medication;
  • Pregnancy. Experiments on animals showed harmful effects in all trimesters of pregnancy, so the people of the experiments was not. So women in this position, the sodium thiosulphate is usually not prescribed;
  • Breast feeding: the drug is administered to nursing mothers only when absolutely necessary;
  • Other medications: the decision for the doctor;
  • Interaction with alcohol and tobacco. It is impossible to smoke tobacco and drink alcohol during use of the thiosulfate;
  • Some disease. The drug is used with caution in hypertension, liver and kidney, edema of lower extremities, diseases of the heart.

Along with useful effects is adverse and sodium thiosulfate. Side effects (often associated with overdose):

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  • Agitation (comes to the fact that people can't stay alone)
  • Blurring the contours of objects (vision change)
  • Hallucinations (person sees, hears or feels illusory objects and actions)
  • Mental Changes (sometimes resembles a psychosis, as is temporarily out of contact with reality)
  • Nausea, vomiting
  • Joint Pain
  • Ringing in the ears.

I must say that the sodium thiosulfate is present not only as a medicine, contained in household chemicals and cosmetics. However, be afraid to use it, because the blood did not fall, so don't get paranoid.

Just discovered another effect of this drug. Sodium thiosulfate is now used to treat patients vessels which calciphilous. A normal calcium is not impaired, which makes extensive use of the drug under consideration. The only issue – nausea and vomiting that appear in the majority of patients. But in this case this side effect can be neglected.

Sodium thiosulfate can be prescribed only by a doctor. Therefore, in this article we do not specify the dose and frequency of use. Patients this exploratory information, and for doctors there are a more detailed reference.


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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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