"Combiner-Duo" applied topically in ophthalmology and otolaryngology practice. The active substance – ciprofloxacin and dexamethasone. Auxiliary substances: mannitol, benzalkonium chloride, hydroxypropylmethylcellulose, edetate disodium, hydrochloric acid, water for injection.
Active component provides antimicrobial ciprofloxacin, dexamethasone-anti-inflammatory effects.
The First active in relation not only to breeding, but standing still gram-negative microorganisms.
Dexamethasone is a synthetic glucocorticosteroid used more as immunosuppressive and anti-inflammatory agent. The component is able to reduce proliferation and capillary permeability, cellular infiltration, local exudation, the activity of fibroblasts and deposition of collagen, inhibit the formation of scar tissue.
Shown in inflammatory processes in the eye, keratitis, subacute and acute conjunctivitis, blepharitis, and other diseases of the eyelids. Assigned to the drug as in anterior uveitis, for the treatment and prevention of various complications after eye injuries, surgeries. "Combiner-Duo" is used in inflammatory diseases of the ear. Is assigned to the drug in the acute form of otitis media (outer and middle).
The drug is Contraindicated in herpetic keratitis, pregnancy, tuberculosis, lactation.
"Combiner-Duo". Manual.
Eye disorders inflammatory disorders recommended one or two drops into the conjunctival SAC. Instillation (instillation) was carried out in six to eight hours. Allowed the physician during the first two days to carry out the instillation every two hours. The duration of therapy from five to fourteen days with blepharitis and acute bacterial conjunctivitis, from two to four weeks at a keratitis. As a preventive measure (after surgery and to prevent inflammation) it is recommended to use "Combiner-Duo" from five days to one month.
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In the treatment of inflammations of the ear the drug is instilled into the external canal (ear) of the affected organ during the week twice a day.
In applying the drug may be a stinging, corneal infiltrates, itchy eyes, redness, conjunctivitis, swelling of the face or eyelids, keratitis, sensation of foreign object in the eye, blurred sight, photophobia, optic nerve damage, glaucoma, dry eyes, infection (secondary), cataract, corneal thinning, rashes on the skin. When you use in ear diseases in some cases, there is discomfort, pain, itching, congestion of the ear.
In case of overdose may develop erythema, petechial keratitis, itching and eyelid edema, increased lacrimation. It is recommended rinsing with water, the discontinuation of the drug, symptomatic treatment.
It Should be noted that prolonged use of the drug contributes to an increase in pressure (intraocular), accompanied by damage in the optic nerve and other negative consequences.
The Use of corticosteroids often exacerbate the symptoms of acute purulent eye infections.
Patients who use contact lenses before instillation remove them; set the lenses back recommended after twenty minutes.
When used "Combiner-Duo" reviews patients often agree that the drug should not be used more than seven days. However, many believe that the drug is quite effective in the postoperative period in the treatment of inflammation of the eye.
The Use of the drug should be done only under the supervision of a specialist.
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Alin Trodden - author of the article, editor
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