Lizobakt – usage instructions

Lizobakt Drug comes in round tablets for sucking. Tablets white or white with a slight tinge of cream or yellow, on one of the sides of the separation risk.

Structure

Active substance:

• Pyridoxine hydrochloride-10 mg (1 table.);
• Lysozyme hydrochloride – 20 mg (1 table.).

Excipients:

• Tragant;
• Magnesium stearate;
• Vanilla;
• Lactose monohydrate;
• Sodium saccharin.

Pharmacological action of the drug I have

Manual says that I have – a local antiseptic and antimicrobial drug which is used in dentistry and ENT practice. In addition, it has a small analgeticski effect that plays, though not too pronounced, but noticeable role in this drug for dental disease.

One of the active substances-lysozyme, a protein enzyme that also is an antiseptic, and in addition it has strong antiviral and protivolakozna activity. In addition, lysozyme has antibacterial activity against gram-negative and gram-positive bacteria.

The Second active substance-pyridoxine significantly enhances the regeneration of the mucosa of the mouth. The pyridoxine can not affect the pharmacological characteristics and properties of the second component of the drug - lysozyme.

Pharmacokinetics

Immediately after applying I have readily absorbed into the bloodstream from the gastrointestinal tract, reaching its maximum concentration after an hour. The drug components are separated in the body so that the greatest concentration of lysozyme accumulates in the mucous membranes, and pyridoxine-in the muscles. Pyridoxine can pass through the placental barrier and be released during lactation with milk.

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After it is finished biotransformation of the active substances of Lekarstva, lysozyme is excreted mostly with urine, as well as pyridoxine.

Indications for use of lizobakt drug

Manual says I have a medicine intended for the treatment and prevention of infectious diseases, which manifest themselves on the mucous membranes of the gums, throat, mouth. This:

• Stomatitis;
• Gingivitis;
• Catarrhal respiratory tract;
• The herpes of the mouth;
• Erosion of the mouth of various etiologies.

The Drug can be used as during pregnancy and when breast-feeding a baby. But you must understand that pyridoxine may stand out with the milk, so during lactation, it is recommended to use the drug only after medical consultation.

Side effects of the drug I have

The statement says that the scientific studies that were carried out by independent companies reveal no serious side effects after taking this drug. But in rare cases may be a manifestation of small allergic reactions to certain components of medication, for example, to the support material.

Drug interaction

A marked potentiation of the effect when combining lisobact and other antibacterial drugs, including penicillin, nitrofurantoin, chloramphenicol.

When using levodopa and lisobact at the same time significantly reducing the antiparkinsonian effect of levodopa.

The Effects of most types of diuretics potenziruetsa in that case, if they are to take along with lysobacter. This is due to the peculiarity of the pharmacological properties of the drug I have.

The user manual says that it is not recommended to use together with lysobacter immunosuppressants, pyrazinamide, effective in, isoniazid, estrogen and contraceptive èstrogensoderžaŝimi drugs because all these drugs are antagonists of pyridoxine and increase its renal secretion.