"Accardo": instructions for use, analogs, reviews

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2018-03-21 01:15:25

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All Known acetylsalicylic acid is widely used as a means of lowering temperature. However, not everyone knows that this medication is often prescribed to patients for the treatment of cardiovascular diseases. In this article we will talk about this drug, as tablets “Accardo”. Instruction manual says that this drugs includes aspirin. Used this drug in cardiology practice for years and is well established as doctors and patients. What tablets “Accardo” help, you can learn in this article.

A Full description of the drug, instructions for use, indications and side effects - all this information is given only for reference and cannot serve as a basis for administration of the drug alone. Such self-medication is harmful to health, and therefore should be taken solely on prescription.

accordal usage instructions

Pharmacological characteristics

The Drug “Accardo” represents the acetylsalicylic acid coated with a shell that dissolves directly in the intestine. It is a nonsteroidal drug with anti-inflammatory effect. The mechanism of action of the drug is that the active component has an irreversible inhibition of COX, resulting in the suppression and blockade of thromboxane A2 synthesis and platelet aggregation. The effect of the active component remains through the week, maximum concentration of drug achieved in the blood 15 minutes after administration. During normal operation of the urinary tract, a single dose of the drug is excreted in the urine within 24 to 72 hours.

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In Addition, high doses of the drug have the ability to numb and relieve fever. Inhibition of the synthesis of platelet allows you to use this medication in the treatment of various cardiovascular diseases.

Who is a drug “Accardo”

Instructions for use describes conditions under which it is recommended the intake of these pills.

Usually the drug is administered for prophylactic purposes, with the threat of acute and repeated myocardial infarction if the patient has risk factors such as diabetes, obesity, hypertension, hyperlipidemia.

Indications are also considered unstable angina, risk of ischemic stroke (including when the rolling circulation of the brain).

The Drug “Accardo” may be assigned to patients for prevention of thromboembolism after operative and invasive interventions on the vessels, such as coronary artery and artemisone bypass grafting, angioplasty of carotid and coronary arteries.

Accardo instruction manual counterparts

Contraindications

Almost all medications have a list of States in which impossible their reception. Not an exception and the pill “Accardo”. The use of this medication is not recommended for persons with disorders such as:

  • Bleeding of the gastrointestinal tract;
  • Erosions, ulcers of the gastrointestinal tract;
  • Bronchial asthma in the stage of exacerbation and remission;
  • Hemorrhagic diathesis;
  • Congestive heart failure;
  • Polyposis of the paranasal sinuses and nose.

It is Strictly forbidden to take the medicine "Accardo" counterparts and similar in composition medications during pregnancy and breast-feeding a baby. A contraindication can be considered as individual sensitivity to acetylsalicylic acid and auxiliary components of preparation, in particular lactose.

Be wary appoint drug in violation of the liver and during therapy with anticoagulants. In the alleged surgical procedures it is also desirable to drink tablets "Accardo”. The instruction on application contains information that caution should administer this drug to people with kidney disease because it is excreted through urine.

These tablets designed for prolonged use. High doses of medication can be prescribed in extreme cases to reduce the high temperature.

Regimen

How to conduct therapy with medication “Accardo”? Instruction manual States that the drug is for oral use. The pill before meals and drink a glass of water.

In the prevention of acute myocardial infarction administered 100 mg daily or 300 mg once every 48 hours. For quick absorption and achieve the concentrations of active substance in plasma tablet is chewed and washed down with water after.

If a drug is assigned to patients with unstable angina or to prevent re-infarction, ischaemic stroke or for prevention of thromboembolism in the postoperative period, the pill 100 mg every 24 hours.

For the prevention of thromboembolism of the pulmonary artery and its branches, and deep vein thrombosis are advised to drink tablets 100 mg once daily or 300 mg every 48 hours.

Adverse effects

Lee is Having a negative impact on the body drug “Accardo" (tablets)? Usage instructions and testimonials indicate the following possible side effects:

  • Hematopoietic system: anemia and increased likelihood of bleeding;
  • Stomach: pain in the abdomen, nausea, vomiting, heartburn, perforated ulcers of the duodenum and of the stomach, increased activity of liver enzymes;
  • Immune system: allergic rash in patches, blisters, urticaria, angioedema and anaphylactic shock;
  • The respiratory system spasm of the bronchial tubes;
  • Central nervous system: hearing loss, noise and hum in the ears, headache, and dizziness.

Such side effects describes to the drug “Accardo" instructions for use, but the reviews indicate that these occurrences are rare and generally the drug is well tolerated.

Use during pregnancy

Why the drug use ‘Accardo during pregnancy and lactation? The answer to this question lies in a simple explanation. Acetylsalicylic acid is considered undesirable substance in the immature body of the child. Among the many contraindications to the drug “Accardo” the statement also includes a paragraph concerning the prohibition of taking the medication to anyone under 18 years of age.

Active substance, reaching maximum blood concentration after administration, able to penetrate to the developing fetus.

Accardo reviews

It is Especially dangerous its effect in high dosages in the first and third trimesters. Treatment with this medicine increases the risk of developmental defects, particularly cleft palate and congenital heart defects.

Tablets “Accardo”, analogs of this drug that contains the same active component, are assigned only when an adequate assessment of the risks and benefits of therapy.

Acetylsalicylic acid in a dose of 300 mg in the last months of pregnancy adversely affects labor and cause premature closure of the ductus arteriosus in the fetus and increases the risk of bleeding during childbirth and cesarean section mother and baby.

Which indicates That the application before the birth of tablets “Accardo" instructions for use? Analogues and the drug immediately before childbirth can cause bleeding in the brain in a child, at special risk group of premature infants. Therefore, such therapy should be abandoned.

Use during lactation

In the period of breast-feeding one-time use of tablets “Accardo”, which reviews say they are well take care of the fever, do not require discontinuation of breastfeeding. But long-term therapy with this medication may cause harm to the body of the baby, so you need to choose between taking medicine and breast-feeding, assessing the woman's condition.

Doctors and patients

Basically, all the responses about the product are positive. Doctors say that the pill is designed to prevent repeat heart attacks, strokes, and thrombosis after surgery and do well with their tasks.

Patients who have undergone the therapy claim that if you do not chew the pill, no stomach discomfort after taking does not occur. The main thing, just stick to the recommended doctor dose. Patients also testified by the fact of positive dynamics in the prevention and treatment of blood clots.

Among the reviews and noted this positive aspect, like pricing. Pills are inexpensive and are drugs a public group.

Accardo analogues

Interaction with other medicines

Taking the drug and analogues of drugs ‘Accardo”, the readings of which are almost identical, you need to be very careful when it combination with other medicines, as aspirin can increase the effects of the individual substances in the composition of other drugs.

So, for example, by reducing renal clearance and ousting him from the blood increases the effect of the tablets "Methotrexate", which is undesirable during chemotherapy with this agent.

The Main component of the drug “Accardo” displaces valproic acid from the blood and thus increases its impact on the body. At the same time it is undesirable to drink tromboliticaskie and antiplatelet medications and pills “Accardo”. Reviews of doctors about this combination say about the negative impact on the human body.

Acetylsalicylic acid enhances action of insulin and its derivatives, it is necessary to consider the people who are watching the sugar levels in the body.

It is Strictly forbidden to take the pill “Accardo” together with preparations containing the substance ibuprofen and its derivatives.

Special instructions about taking the pills “Accardo”

Instruction manual, a photo of which is presented in the article is the original version of the description of the drug from the producers, which is attached to each package. It contains all the data relative to the recommended dose described pharmacological action, indications and side effects. And although this drug is released in pharmacies without a doctor's prescription, do not recommended to seek independent long-term treatment with this medicine. Also, special attention should be given to a single reception for reducing the temperature of the body, especially those patients who have problems withthe hematopoietic system.

It is Strictly forbidden to take the drug “Accardo” together with alcohol as this combination will have a negative impact on the gastric mucosa and can lead to serious disease.

In patients with asthma, aspirin can cause bronchospasm and provoke an asthma attack therefore, before taking the pill “Accardo”, should evaluate the benefits and the risks of the drug.

The Drug does not affect concentration does not cause inhibition and drowsiness, and therefore patients during therapy can drive vehicles and to produce work of high risk.

Overdose

The one-time Excess dosage can cause bleeding in the stomach. Symptoms of overdose include nausea, vomiting, roaring in the ears, cardiovascular and respiratory failure, which can cause coma patient. With a strong overdose may develop fever, respiratory alkalosis, ketoacidosis and hyperventilation. Under such conditions required the adjustment of daily and single dose of the drug, and in some cases cancellation and symptomatic treatment. For removal and neutralization of the action of the active component of the drug “Accardo” is an emergency treatment: gastric lavage, hemodialysis, the introduction of absorbent substances and determination of acid-base balance for subsequent diuresis.

Storage and release form

How to store medication “Accardo”? Instruction manual, reviews of the drug indicate that it does not require special conditions for storage of tablets. Just follow the General recommendations contain a package of pills in a dark and dry place at temperature not above 25 degrees. In such circumstances, the medication will retain its medicinal properties for over three years.

Produced tablets “Accardo” in a different dosage of the active ingredient: 50, 100, and 300 mg. as the main active ingredient acts as acetylsalicylic acid. The same auxiliary ingredients are corn starch, povidone, microcrystalline cellulose, talc, magnesium stearate, lactose, titanium dioxide and castor oil.

Tablets are round biconvex shape and equipped with a shell that dissolves only in the intestines, which prevents undesirable effects on the gastric mucosa.

Similar drugs

drug Accardo

That says replacing the drug “Accardo" instructions for use? The counterparts must contain the same active ingredient and same effects on the body. Substitutes there may be such drugs as “Aspirin”, “Aspirin”, “KARDi ask”, “Thrombotic ass” and “Aspirin Cardio”.

Each of these medicines has its regimen and the recommended dose. Counterparts, as well as the drug “Accardo”, which consists of acetylsalicylic acid, not used in Pediatrics, have a number of contraindications and prohibitions on the combination with other drugs.

During the therapy is necessary to systematically monitor the condition of the blood, and to monitor the presence of blood in the stool of the patient. For this it is necessary periodically to conduct clinical tests, the results of which should determine further treatment.

The Drug “Aspirin”:

The Therapeutic properties of this drug lies in its ability to remove heat, subdue inflammation and reduce the adhesion of platelets. Indications for therapy are fever with SARS and influenza, prevention of infarction and thrombosis, and rheumatic diseases.

The pill inside for analgesic effect for 325, 400, 500 mg for antiplatelet effect of 50, 75, 100, 300, and 325 mg.

When the fever and pain adults the recommended to drink the remedy in the dosage of 100 mg Effervescent tablets dissolve in water and drink after meals. Single dose should not exceed 1 g of active substance. If the drug designated for prophylaxis of thrombosis, the dose should be 40–325 mg once in 24 hours.

This drug has the same contraindications and side effects as a means of ‘Accardo”.

 Accardo evidence

The Drug ‘Thrombotic ass”:

The Medication called “Thrombotic ass" is identical on action and composition analogue drugs ‘Accardo”. In appearance it is round and convex on both sides of the tablets with a shiny and slightly rough surface. Active substance – acetylsalicylic acid in a quantity of 100 mg in one tablet. Accessories – lactose, silicon dioxide, triacetin, talc, potato starch, silicone antifoaming agent, methacrylic acid and the copolymer of metacrilato.

The drug is Sold in packs of 3 blisters, each containing 10 tablets. The recommended dose of 50-100 mg at a time. However, your doctor may prescribe a higher dose considering patient condition and contraindications.

Medication “Aspirin”: application features

Accardo application

The Peculiarity of this drug is that it has no enteric shell, but because these pills irritate the gastric mucosa. This fact makesimpossible medication for ulcers of the gastrointestinal tract in the acute stage. This medication is contraindicated in children under 15 years of age.

It is Recommended to drink tablets for the prevention of thromboembolism, heart attacks and strokes, and rheumatism, infectious and inflammatory diseases. The dosage is selected individually. The official instruction manual includes recommendations for regimens. The dose may vary from 40 to 100 mg at a time, but not more than 8 g of active substance per day.


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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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