In essence, the oncotic pressure (osmotic) — are compounds that dissolve in the formed elements of blood and blood plasma. The shortage of proteins in the body it is reduced, which can lead to the fact that due to the accumulation of fluid will start to appear edema. This is because the membrane walls of blood vessels are semi-transparent and semi-permeable. They are well and freely pass the water and ions and molecules of different substances – worse.
Normal oncotic pressure is about 7.5 ATM. (5700 mm Hg or 762 kPa). Activity of the plasma varies in the area of 290 mOsm/L.
However, the osmotic pressure is not measured by the number of dissolved molecules, and their concentration. A large part of the plasma ions (99,5%) are inorganic ions the concentration of which depends on oncotic pressure. The pressure of the plasma proteins is only a small part, only 0,03-0,04 ATM. (25-30 mm Hg). But it is worth remembering that the pressure exerted by proteins plays a critical role in the distribution of water between the plasma and key tissues.
This part of the procedure and consider the identification of oncotic pressure. His participation in the distribution of water is indicated by the fact that capillary walls are mostly impenetrable to proteins. In the tissue fluid protein is much less, therefore their concentration gradient on both sides of the capillary.
Due to the high oncotic pressure of fluid in the intercellular space does not accumulate and circulates.
For the prevention of oncotic pressure recommended therapy of preeclampsia, which is fairly wide, so the result will not keep itself waiting. With normal content of proteins in normal blood clotting it is sufficient to reduce the risk of heart disease.
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The Oncotic pressure of blood is usually kept at a constant level. In its neurohumoral regulation involved the organs of excretion, such as sweat glands and kidneys. Decrease or increase in oncotic pressure is perceived as on the periphery of the vessel walls and in the Central part (the hypothalamus), where it secretes the hormone antidiuretic, which affects the process of absorption in the renal channels. Its function is to regulate the process of urine formation. The stability of the osmotic pressure provide ADN, aldosterone, prohormone, hormone frencesco heart.
Reflex takes place in secreting organs change activities, or lead to excessive delay, or a sudden loss of fluid and salt in the body. In these processes the first and the leading role goes to proteins (oncotic pressure), which is able to bind and give ions. Through the activities of the secreting organs (kidneys and sweat glands) metabolic products, which are constantly formed in the body, most of them do not have any negative effects on the osmotic pressure.
Violations of level oncotic pressure associated with an imbalance of plasma total protein, albumins and globulins, anions, cations, sodium, potassium, calcium and other components. This can be caused by various pathological conditions and diseases (intoxication, burns, postoperative period, shock, bleeding, various diseases, etc.). In such cases, it is important to regularly check the oncotic pressure. Treatment is primarily aimed at eliminating underlying disease and restoring the balance of salts in the blood plasma. However, before curing pressure, oncotic especially, be sure to consult your doctor. Do not self-medicate!
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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."
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