Drug "potassium Chloride"

The Drug “potassium Chloride” is a tool that is intended to replenish the deficiency of potassium in the body. This salt, which is either colorless or has a white color, it can be in the form of powder, solution, or in pill form, it is also used in the production of chemicals such as potassium hydrochloride and potassium carbonate.

That potassium is the main intracellular ion that performs a big role in ensuring the regulation of different body functions. This element is involved in the holding and transfer of organs innervated by the nerve impulse, in the process of contraction of skeletal muscle, in maintaining intracellular osmotic pressure and many other biochemical processes. It also reduces the conductivity and excitability of the myocardium, and its presence in high doses, inhibits automaticity.

After the drug “potassium Chloride” ingested, approximately 70% of its passively absorbed due to the fact that the concentration of potassium is much higher in the lumen of the small intestine than in the blood. In the colon and the ileum, the trace element is released into the lumen of the intestine, it is coupled exchange with sodium, after which about 10% excreted in bile.

Medicine “potassium Chloride” - the dosage

Single dose should not exceed 25-50 mEq of potassium, whereas the daily dose may not be higher than 50-100 mEq of potassium. The course of treatment and frequency of this drug depends on the evidence. If necessary, the introduction of means “potassium Chloride” intravenous drug dose and treatment regimen in each case is determined separately.

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Drug interaction

If we assume the simultaneous use of table salt substitutes, potassium-sparing diuretics and other drugs potassium, you are at great risk of hyperkalemia.

When the need arises for the introduction of this drug to a pregnant woman, it is necessary that the physician evaluated the expected benefit to the mother and the alleged risk to the fetus. When breastfeeding should use of the drug to abolish the fed.

Possible side effects

Signs of hyperkalemia are usually muscle weakness, paresthesia in the lower and upper extremities, arrhythmia, heart block and stop the confusion.

If you are taking the drug “potassium Chloride” inside, it may cause nausea, vomiting, and diarrhea. Also, in some cases, may occur ulcerative lesions of the stomach and small intestine, often accompanied by bleeding and perforation, and later formed the stricture.

After intravenous administration of this drug may develop disorders of the heart.

Indications for use

The Cure “potassium Chloride" is assigned in the presence of hypokalemia, of any origin, including after severe vomiting or diarrhoea, with polyuria and chronic renal failure. It can also be caused by taking certain medications can occur when glycoside intoxication, or if hypokalemic paroxysmal form of mioplegii.

Contraindications

The Drug is not indicated for the presence of violations of renal excretory function, in complete heart block. Also it should not be used when hyperkalemia, metabolic violations in the form of acidosis, hypovolemia with hyponatremia in the presence of gastrointestinal diseases, which are in the acute stage, and adrenal insufficiency.

The substance is potassium chloride lethal dose is more than 5 grams, when the need for anesthesia during surgery pretty much 100—150 mg. If the drug is injected intravenously and too quickly, developing hyperkalemia, which can lead to the death of the patient. Thus it is necessary to know what to it can develop very quickly and without showing external symptoms. In case of overdose it is necessary to introduce the solution of sodium chloride orally or intravenously, or intravenously 300 to 500 ml of dextrose in 1000 ml containing 10-20 units of insulin.