"Palin": instructions for use, indications, side effects. The best analog "Palina"

Urinary tract Disease will not be bothered if the kit is the drug "Palin". He acts quickly and efficiently. The result is noticeable after the first application. Analogue “Alina” “Furadonin” is similar, but has a different active ingredient.

Composition and form drugs

The Drug "Palin" produce in the form of capsules, tablets and suppositories. The active ingredient of the medicine acts pipemidova acid. In capsules contains 200 mg tablets 400 mg and suppositories 200 mg.

The Capsules are Packed in blister packs of 10 pieces. In a cardboard box two blister. Tablets are Packed in plastic bottles of 20 pieces. The box contains one bottle. Vaginal suppositories are Packed by 10 pieces in squeaks. The cardboard packaging 1 creaking.

The Analog of “Alina” “Ofloxacin” is not only in tablets but also in the form of ointment, solution for infusion.

Pharmacological action

"Palin" is an antibacterial drug and belongs to the group of quinolones. Active against gram-negative bacteria, such as:

• Pseudomonas aeruginosa.
• Proteus vulgaris.
• Klebsiella pneumonia.
• Proteus mirabilis.
• Escherichia coli.
• Neisseria spp.
• Enterobacter spp.

Once the drug is effective against gram-positive bacteria, for example Staphylococcus aureus, and is active against some strains. Is Acinetobacter spp. Providencia stuartii, Klebsiella spp., Alcaligenes spp. The drug has no effect on anaerobic microorganisms. Resistance of bacteria against pipemidova acid is developing quite slowly.

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The Drug "Palin" is widely used in urological and gynecological practice. Its active substance is pipemidova acid, which is characterized by bacteriostatic and bactericidal properties.

The Mechanism of action of the drug is based on the ability pipemidova acid molecule to suppress bacterial DNA-topoisomerase II, normalizing transcription, repair and replication of DNA of bacteria. When used in high doses the drug gives pronounced bactericidal effect, in low doses has bacteriostatic action.

After ingestion, the tool absorbed the gastrointestinal apparatus. The highest concentration of the active substance occurs after 1-2 hours after consumption of “Alina”. This drug has a low degree of connection with the blood supply, about 30% or less. The drug is not metabolized in the human body. Excreted renal the body by creating in the urine high concentrations of the active component. The day goes from 50 to 85 % of the drug, the accepted dosages. A small part pipemidova acid goes through the intestines in an unchanged form.

The Analog of “Alina” “Protracted” is similar on the body. He, as well as the first drug, contains in its composition pobedimova acid.

"Palin": indications and contraindications

The Drug "Palin" of the prescribed for inflammatory processes in the urinary system and pelvis. Pathology can have both acute and chronic. Caused by microorganisms sensitive to this drug. This diseases such as urethritis, pyelonephritis and prostatitis. Helps "Palin" from cystitis. The drug can be used in complex therapy in the treatment of certain gynecological diseases.

The Drug "Palin" are used to prevent relapses of chronic diseases of urinary system. It is also used for prevention of infectious complications that can occur when instrumental surveys, and also for various procedures in urological and gynecological field.

The Analog of “Alina” “Pimidel” has the same indications for use drugs and, if necessary, can replace the first medicament.

A Contraindication to the use of drugs "Palin" is an individual intolerance of the active substance and minor ingredients of the medication. Do not take the drug during epilepsy, and pathologies of the Central nervous system, accompanied by convulsions. Not prescribe medication in renal failure, when creatinine clearance less than 10 ml/min. the Prohibition to the use of medication is liver failure, especially hepatitis chronic or active form, as well as cirrhosis of the liver.

A Contraindication is porphyria, the disease is inherited and is accompanied by the failure of hemoglobin synthesis. Is not recommended drug for pregnant and lactating women, and children, whose age has not reached the age of fourteen.

The Drug is not prescribed to elderly people over 70 years of age and persons with hypersensitivity to acetylsalicylic acid, drugs hinolonovogo series.

Medicine "Palin": usage instructions

The Price of this drug is around 200-250 rubles. Despite the fact that the medicine can buy in the pharmacy without a doctor's prescription, it should not be made independently, without doctor appointments.

The Drug is consumed orally. Tablets and capsules do not chew, but swallow whole with plenty of water(about 250 g). During treatment you should drink two liters of fluid a day and keep track of the volume of urine. In the treatment medication you should not sunbathe, moreover, we should try to avoid direct UV irradiation. If the treatment with this drug will be delayed for a long time, then periodically, you need to have a blood test to monitor liver organ and kidneys by biochemical analysis of plasma.

Should be used in accordance with the doctor's medicine "Palin". The dosage for adults is 400 mg a day split into two doses twelve hours. There are situations (staph infection), when "Palin" is administered in a higher dose of 200 mg three times a day. In this case, the interval between doses of medicine equal to eight hours.

The Duration of the therapeutic course is determined by the doctor individually for each patient. The average duration of treatment is ten days. If necessary, medication can be used up to 6-8 weeks.

It Warns that people with severe malfunction of the kidneys the dose should be adjusted when applying the medication "Palin" of the instruction manual (the price of drugs affordable and lower than some peers, for example, “Nevigramon”).

Women when taking tablets or capsules can optionally be assigned to vaginal suppositories to be applied once a day at night. Treatment they last up to 7-10 days.

When using ‘Alina” together with antacids and sucralfate may decrease absorption pipemidova acid in the digestive tract. If you cannot abandon to their comprehensive use, it should withstand the gap between the medication is 2-3 hours.

Long use of ‘Alina” together with theophylline and caffeine increases concentration of the latter components in the blood. "Palin" enhances the effect of cimetidine, warfarin, rifampicin, as well as nonspecific anti-inflammatory drugs.

If "Palin" taken simultaneously with antibiotics-aminoglycosides, there is a stronger bactericidal effect on microorganisms.

When used together, “Alina” with other medicines belonging to hinolonam as well as complex application with non-narcotic means of pain nature increases the likelihood of seizures.

The children "Palin" can cause an increase in muscle tone. Even pipemidova acid tends to accumulate in cartilage.

For children over the age of fourteen, the drug is applied in the same dosage as for adults. Children under the age of fourteen years, the drug is not prescribed.

Side effects overdose

In drug treatment, "Palin" side effects from time to time may occur. From the digestive apparatus, sometimes patients suffer from nausea, a gag reflex, diarrhea, gastralgia. In rare cases, there may be pseudomembranous colitis, accompanied by severe diarrhea.

During the application “Alina” there are negative effects from the nervous system. It is a headache, a disorder of the visual apparatus, excessive excitement, depression, confusion, hallucinations.

Patients may experience tremor of the extremities, seizures. In some cases, there is sleep disturbance.

During the therapeutic course happens to be a violation of the hemopoietic system. In individuals with deficiency of glucose-6-phosphate dehydrogenase may occur with hemolytic anemia. When taking the drug there have been cases with the development of eosinophilia. The elderly sometimes disturbs thrombocytopenia.

The use of tablets (capsules) was recorded allergic reactions such as itchy skin, rashes on the skin, Stevens-Johnson syndrome.

Among other negative reactions people were worried about the photosensitivity, there is resistance and superinfection.

If the drug is taken in doses exceeding those stated in the instructions, it may be an overdose of a drug. It stands symptoms of nausea, headache, vomiting, dizziness, tremor and cramps of the extremities, confusion.

If after the use of the drug has passed more than four hours, you need to make gastric lavage and drink activated charcoal. If negative reactions appeared in the region of the Central nervous system, we administered symptomatic therapy. To withdraw the medicine from the body forced diuresis helps.

Special instructions

The Cure "Palin" must be carefully prescribed to patients suffering from disorders of cerebral circulation in amaze. This also applies to bleeding in the brain, as well as spasms of the brain vessels. Also with caution should use the "Palin" people whose age have crossed the border for 70 years.

Passing therapeutic course, patients should drink plenty of pure water, two liters a day. Constantly need to monitor the urine output. Because of the risk of photosensitivity when used in medicine it is necessary to avoid ultraviolet radiation.

People allergic to chinolone should exercise caution whenthe use of “Alina”, because there is a likelihood of cross-sensitivity.

When prolonged treatment is necessary to monitor General blood counts. See the work of the liver organ and kidneys. From time to time to check the susceptibility of the microflora to the active ingredient of the drug.

When you use ‘Alina” there is a decreased probability of a false positive urine glucose when using Benedict's reagent or composition of Felling. As a result, recommend the use of enzymatic reaction with glucose oxidase.

While taking medicines need to refrain from the threat of activities related to high concentration of attention and requires speed of reaction.

Many people ask: "Palin" - antibiotics or not? This drug is an antibiotic, therefore, its use should not drink alcohol in order to avoid negative reactions.

Counterparts

It has been Above told about effect of the drug is "Palin". How to take it, more will be told by the instruction manual. Now a little about the analogues of medicines which are used when the treatment of ‘Palin" was ineffective or caused adverse reactions. The most common substitutes that are similar in composition, are:

• «Vero Piperidin».
• «Papagal».
• «Unopened».
• «Pimidel».
• «Pipes».
• «Pipeline».
• «Protracted».

Often called "Palin" replace drugs that have a different composition, but act in a similar way. The most popular of them yavlyayutsya:

• «Ofloxacin».
• «Cameron».
• «Nolicin».
• «Furagin».
• «MONORAL».
• «Nitroksolin».
• «Furadonin».
• «Tsiprolet And”.
• “Furamag”.

These and other analogues able to replace "Palin" if necessary, but to get they must only by a doctor.

Analogue “Ofloxacin”

One of the most accessible analogs “Alina” is “Ofloxacin”. The price is around 70 rubles for 10 tablets. Produce the drug in Russia. Active substance-ofloxacin in one tablet it contains about 400 mg.

The Drug has a wide range of applications and shown in various infectious diseases. It is a disease of the respiratory tract, ENT organs, urinary system, kidneys, pelvis, genitals, etc. it Has bactericidal and antibacterial effect.

It is better to accept the - ‘Palin” or “Ofloxacin», - tell a doctor. Both drugs are antibiotics, but the second has a more extensive range of applications. In this regard, doctors often assigned to "Ofloxacin”. The price is an additional advantage.

“Kanefron” substitute “Alina”

The‘Kanefron”, “Palin" can be used for the treatment of diseases of the genitourinary system. But it differs from ‘Alina” in its naturalness. Part medications part herb centaury, lovage rhizome and leaves of rosemary. The natural content of the drug helps to avoid many side effects, but treatment them longer. Is this drug from 350 to 400 rubles per 60 tablets. Made in Germany.

For Adults the drug is prescribed 2 tablets 3 times a day, that is 6 pills a day. “Kanefron”, it is recommended to take 2 to 4 weeks. Packing only enough for 10 days of treatment. Treatment costs more than cure "Palin".

“Palin” and “Kanefron” have the same indications for use and can be used together in the treatment of cystitis. The first is an antibiotic, and the second is completely natural. Taking them together is very effective, as medications reinforce each other's action. Many doctors use in their urological practice exactly this combination.

Substitute “Nolicin”

“Nolicin” - another drug that can replace "Palin" if necessary. Made in Slovenia. Price of 10 tablets - about 130 rubles. The active ingredient-norfloxacin. In one pill it contains about 400 mg.

The Drug “Nolicin” has a wider range of application than the "Palin". Patient testimonials say that it does effectively the last of the specified drug. In the treatment possible side effects. Therapeutic course lasts from 7 to 10 days. Together with him, recommended to drink probiotic.

What to choose for the treatment of - “Palin” or “Nolicin”? That the doctor should decide based on the condition of the patient and the severity of the disease. It is impossible to self-medicate and choose the drug for the treatment of diseases of the urinary tract on their own. So you can not only start the disease, but also to buy serious side effects.