Diakarb, instructions for use, side effects, contraindications

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2018-03-26 18:55:10

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"Diacarb" release in the form of tablets. The active ingredient of the drug is acetazolamide (250 mg in 1 tablet), which belongs to the group of diuretic drugs.

Pharmacological action of "Diacarb" is based on the ability to ingibirovat carbonic anhydrase. Acetazolamide diuretic effect, increases the urinary excretion of ions (sodium, potassium, bicarbonate). "Diacarb", the instruction specifies not affect the amount of chloride ions in the urine, and shifts the pH of the urine increase. The concentration of acetazolamide in the body depends on metabolic acidosis. By inhibition of carbonic anhydrase "Diacarb" reduces the secretion of aqueous humor, reduces intraocular pressure. The anticonvulsant effect of the drug has suppressing the activity of carbonic anhydrase directly in the brain.

"Diacarb", the statement indicates, is absorbed by the red blood cells, kidneys, muscles, tissues of the eyeball, the Central nervous system. In the process of metabolism of the active substance reacts with plasma proteins, has a penetrating ability through the placenta.

Independently in the body acetazolamide is formed.

"Diacarb", indications for use

The Drug is prescribed:

The edematous syndrome, mild or moderate severity, with alkalosis;

Glaucoma in primary or secondary form, in the period of an acute attack;

In epilepsy "Diacarb" is introduced into the composition of complex therapy;

At mountain sickness.

Dosing of the drug is determined by the doctor depending on the patient's condition and type of disease.

"Diacarb", manual side-effect

Central and peripheral nervous system in rare cases react to the drug with convulsions, paresthesia, tinnitus, myopia; prolonged use occasionally observed cases of disorientation, disturbances in the feeling of sleepiness.

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In the hematopoietic system was seen  in a few cases the changes that occurred as the result of prolonged use, which was manifested by hemolytic anemia, leukopenia, agranulocytosis.

The Possible violation of water-electrolyte metabolism, acid-alkaline environment, expressed: hypokalemia, metabolic acidosis.

"Diacarb", the use of which is lengthy, can provoke, in rare cases, disruption in the urinary tract, which is manifested by nephrolithiasis, transient hematuria, and glucosuria.

Digestive system is sometimes exposed to the risk of anorexia and prolonged use of the patients complained of nausea, vomiting, and diarrhea.

Dermatological allergic reactions manifested by skin flushing, itching, urticaria.

In some cases any muscle weakness.

"Diacarb", instruction contraindications

It is Forbidden to prescribe the drug:

In acute renal failure;

 liver nedostatochnosti;

 gipokaliemii;

 aldose;

 gipokortitizma;

 Addison's disease;

 uremia;

 diabetes;

 pregnancy;

In lactation period;

If you are sensitive to any component of the drug.

To Assign "Diacarb" edema of hepatic and renal origin caution. Close supervision of a doctor is necessary when combined with acetazolamide acetylsalicylic acid in high concentration.

"Diacarb", the statement indicates has special instructions to the destination. If the drug in the treatment of the patient is used for more than five days, there is a risk of metabolic acidosis.

Appointing the drug for a long course of treatment, you need to follow the analyses of peripheral blood, indices of water-electrolyte metabolism, balance the acid-alkaline environment.

"Diacarb", used in high doses, causes signs of sleepiness, fatigue, dizziness and disorientation. Therefore, during treatment patients is not recommended to operate heavy machinery and transport.

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