The etiology of sarcoidosis and what diseases are confused with the syndrome Lefgren

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2018-05-22 22:00:35

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The Syndrome Lefgren – it is a symmetrical increase in basal bronchopulmonary nodes of the lymphatic system on both sides. The disease is accompanied by cutaneous manifestations (erythema nodosum), high body temperature and arthralgia. These symptoms are typical of sarcoidosis.

syndrome legrena

The condition affects different organs - lungs, spleen, lymph nodes. Syndrome Lofgren sarcoidosis is not passed and is not an infectious disease. Do not confuse the disease with cancer processes and tuberculosis.

Clinical picture

Sarcoidosis was quite a while a rare disease, but today the picture has changed, the pathology is spreading with great speed all over the world. According to the statistics most affected by the syndrome Lefgren women from 20 to 40 years, but the disease can come to anyone.

It can Occur without symptoms, gradually or in an acute form. Clinic: asymptomatic, usually detected by chance in prophylactic fluorographic examination. The most common is a gradual flow and progression of the disease with the following characteristics:

  • Shortness of breath on exertion;
  • Dull pain in chest;
  • Pain between the shoulder blades;
  • Dry cough;
  • Low-grade fever;
  • Fatigue and weakness;
  • Increased sweating
  • Loss of appetite;
  • Joint pain in the lower back.

lefgren syndrome sarcoidosis

The Acute course of sarcoidosis is called a syndrome Lefgren, it is accompanied by fever up to 38-39 °C, joint pain, skin lesions in the form of erythema, pain in the chest and shortness of breath. There are cases in acute period of full recovery of the person without the use of drug therapy and other interventions.

Disease Etiology

To the end of medicine unknown causes of this disease, it is likely that provoke its development are the following factors:

  • Infection, mycobacteria tuberculosis, hepatitis C virus;
  • Adverse external factors, inhalation of metal dust;
  • Smoking, which is not the root cause, but significantly complicates the course of the disease;
  • Heredity.

Prevention of sarcoidosis

Patients with syndrome Lefgren it is important to stop Smoking to expedite recovery. Required every 2 years to examine the organs of the chest. Taking into account the fact that the etiology of the disease are unknown until the end, the principles of preventive measures have not been developed. Experts recommend avoiding contact with metal dust and foci of infections.

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Lofgren Syndrome sarcoidosis revealed the following extrapulmonary localization process – lesion of the subcutaneous tissue, skin and peripheral lymph nodes. There is an increase in the cervical, subclavicular, axillary and inguinal nodes. In some cases it affects the lymph nodes of the abdominal cavity.

syndrome lefgren classic example

Bone and the Central nervous system is affected much less, but this disease occurs heavier. Sarcoidosis of the heart found in 20-30% of cases and asymptomatic. The left chambers of the heart decrease in volume, the right ventricle increases.

Early screening and treatment give chances to achieve a favourable outcome. In another case there are changes in lung tissue that eventually leads to disability.

Lofgren Syndrome: acute variant of sarcoidosis

Sarcoidosis is Often confused with tuberculosis because of the similarity of symptoms. It requires careful examination, because the causes and treatment are different. In any case, you can't treat yourself, especially to take drugs for TB patients, this can lead to death.

The Syndrome Lefgren (classic example) - this is when the General condition of the patient is satisfactory. There are changes in the skin. May appear:

  • Papules and plaques;
  • Ozdoblennya erythematosus;
  • Keloid scars;
  • Infiltrates;
  • Erythema nodosum;
  • SKD and CKD sarcoid Beck;
  • Multiple dense nodes in the subcutaneous tissue.

Diagnostics

Patients syndrome Legrena is to conduct radiography. As a specifying method using computer tomography. Conduct biochemical and General blood analysis.

lefgren syndrome is an acute variant of sarcoidosis

The Goal of treatment is to suppress the inflammatory process. The most effective way is the use of corticosteroids for six months. With the defeat of vital organs required glucocorticosteroid hormonal therapy.

Rapidly progressive course treated with short courses of intravenous anti-inflammatory drugs. In cases where the therapy is powerless, is plasmapheresis (blood purification). At severe stage of lung disease need a transplant. The disease and the treatment outcome was generally favourable, it is necessary not only to start the process.


Article in other languages:

AR: https://tostpost.com/ar/health/7436-lefgren.html

BE: https://tostpost.com/be/zdaro-e/13291-etyyalog-ya-sarkoidoza-yak-ya-zahvorvann-blytayuc-z-s-ndromam-lefgrena.html

DE: https://tostpost.com/de/gesundheit/13298-die-tiologie-der-sarkoidose-und-welche-krankheiten-verwechselt-mit-dem.html

ES: https://tostpost.com/es/la-salud/13306-la-etiolog-a-de-la-sarcoidosis-y-qu-enfermedades-se-confunden-con-el-s.html

HI: https://tostpost.com/hi/health/7440-lefgren.html

JA: https://tostpost.com/ja/health/7436-lefgren.html

KK: https://tostpost.com/kk/densauly/13295-etiologiyasy-sarkoidoza-zh-ne-anday-aurular-shatastyrady-sindromy-lefg.html

PL: https://tostpost.com/pl/zdrowie/13289-etiologia-sarkoidoza-i-jakie-choroby-mylone-z-zespo-em-lefgrena.html

PT: https://tostpost.com/pt/sa-de/13281-a-etiologia-da-sarcoidose-e-que-a-doen-a-confundida-com-a-s-ndrome-de-.html

TR: https://tostpost.com/tr/sa-l-k/13297-sarkoidoz-etyolojisi-ve-hangi-hastal-klar-ile-kar-r-sendromu-lefgrena.html

UK: https://tostpost.com/uk/zdorov-ya/13291-et-olog-ya-sarko-dozu-yak-zahvoryuvannya-plutayut-z-sindromom-lefgrena.html

ZH: https://tostpost.com/zh/health/8085-lefgren.html






Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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