The syndrome of Miller Fisher: symptoms, treatment, life expectancy

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2019-03-28 05:20:27

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One of the varieties of the rare Guillain-Barre syndrome, which is an offshoot from a clear picture of what is happening in the body of a diseased person is the syndrome of Miller Fisher. It is characterized by a triad of symptoms, which manifest themselves equally in all patients.

the Miller-Fisher syndrome

Definition

Guillain-Barre is a rare phenomenon. In medical practice, its indices are 1-2 people per hundred thousand population. Often manifests in males and has two peaks of its activity:

  • Young age – 20-24 years;
  • Elderly – 70-74 years.

It is well known to neurologists and has a number of characteristic features, as evidenced by the tests of the cerebrospinal fluid. In addition to the classical course of the disease, the syndrome Miller Fisher described the American neurologist in 1956.

the syndrome of Miller Fisher

Symptoms

The Disease is extremely rare and refers to an acute inflammatory autoimmune diseases in which affects the myelin nerve sheath. At the beginning and in further development of the syndrome of Miller Fisher always is the same and consists of the following number of characteristic symptoms:

  • Areflexia - there is a sharp decline, and in the future and the absence of reflexes of extremities;
  • Ataxia – cerebellar disorders;
  • Ophthalmoplegia-paralysis of the eye muscles, usually the outer, but in difficult cases and internal;
  • Trapes and paralysis of respiratory muscles – develop in severe, advanced cases.

At the correct determination of symptoms and timely beginning of treatment, the disease is benign, does not cause complications and often ends with spontaneous recovery.

the Miller-Fisher syndrome symptoms

Causes

If timely treatment to the doctor for a few weeks or months, you can cure the syndrome of Miller Fisher. To how many live with a similar disease, has not been exactly clarified, as not clear and the reasons for its appearance. But for most people with this diagnosis experts promise the most favourable forecasts. Complete restoration of all functions in the body with proper and appropriate treatment takes a maximum of ten weeks. And only a small number of patients with advanced cases require some additional medical measures.

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Health officials said that often the cause of development of this pathology becomes a normal vaccination. In some cases it was detected after a difficult viral diseases, sometimes the symptoms are manifested after long-term treatment of a number of complicated infection. Famous and familial cases of the disease, suggesting a genetic predisposition of the organism to this disease.

the Miller-Fisher syndrome how to live

Clinical parameters

Leading to the complaint offered by the patient, first and foremost be expressed in the following aspects:

  • Weakness, loss of strength, lack of energy, dizziness;
  • Difficulty chewing, a little later, and with it;
  • Difficulty in walking and self-service;
  • Frequent numbness of hands and feet, undulating pain in the limbs.

It is a descending paralysis – violation of the eye movement, and further, the other extremities (the feeling of the presence of gloves on hand) displays the syndrome of Miller Fisher. The symptoms are very similar to the syndrome gane-Barre, but this kind of pathology is observed paralysis of upward character – from the lower body to the upper.

In Addition to the weakness of the eye muscles, lack of coordination and complete loss of reflexes in a patient is disclosed and a number of minor symptoms, facilitating more precise diagnosis.

  • Temperature sensitivity of the skin below.
  • The Patient is practically not sensitive to pain.
  • Swallowing saliva becomes difficult.
  • It's intermittent, difficult to pronounce words.
  • The Gag reflex is absent.
  • Complaints about problems with the bladder.

Symptoms such as muscle weakness and difficulty in speaking may arise spontaneously. They clearly indicate serious complications and require immediate specialist advice.

the Miller-Fisher syndrome treatment

Diagnostics

To accurately identify the syndrome of Miller Fisher is required to hold a number of necessary studies.

  1. Mandatory trip to the neurologist who conducted the examination and detects all possible violations neurological in nature.
  2. Shown a lumbar puncture. In most cases it identifies the high protein characteristic of this disease.
  3. Analysis of PCR – allows you to decide on the possible causative agent. It could be herpes virus, Epstein-Barr, cytomegalovirus, and others.
  4. Often specialist further assigns a CT scan to help identify possible comorbidities neurological in nature.
  5. It Seems mandatory blood test showing presence of antibodies antiganglioside. This is a clear indication of the presence of the inflammatory process, the positive result of this analysis, it is accurateconfirmation of the diagnosis.

The Syndrome of Miller Fisher requires a comprehensive and the most accurate diagnosis, apply electroneuromyography, differential analysis comparing the symptoms with a number of similar diseases.

the Miller-Fisher syndrome

Therapy

Treatment of this disease includes a complex of measures aimed at suppression of the immune response and cleanse the blood of antibodies. The right to a supportive and symptomatic therapy allows for short time to completely eliminate the syndrome of Miller Fisher. Treatment under the guidance of an experienced specialist leads to the most positive results and full recovery. In very rare cases (three per cent of the total) relapses, suggesting a further course of combination therapy.

  1. Assessment of the respiratory system, in cases where the patient is difficult to move independently, assigned the hospital with constant medical supervision.
  2. During the first five days (no later than two weeks after the first detection of symptoms) is assigned to plasmapheresis and immunoglobulin.
  3. To prevent possible venous thrombosis using anticoagulants.
  4. Requires constant monitoring of blood pressure, as his swings can lead to serious complications.
  5. Advanced classes with a speech therapist.


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DE: https://tostpost.com/de/gesundheit/30937-miller-fisher-symptome-behandlung-lebenserwartung.html

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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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