The H. pylori and eradication therapy

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2018-03-20 20:40:08

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Helicobacter pylori (H. p.) is a gram-negative bacterium concave or spiral shape that lives in the gastrointestinal tract of humans and perhaps some primates. eradication therapyIt has 4-6 flagella, which moves according to the type of corkscrew, embedded under the mucous membrane of the stomach and duodenum, there are also data and about the possibility of colonization of the epithelium of the oral cavity, pharynx, esophagus and rectum. The biochemical properties of this bacterium are the isolation of active enzymes-urease, protease, alkaline phosphatase, oxidase, catalase, gamma-glutamyl transferase. It is these enzymes that determine its pathogenic effect on the mucous membrane of human organs and cause inflammation in gipersecretornye type: gastritis, bulbit, duodenitis, which subsequently may lead to development of peptic ulcers. In this regard, in medicine, began to develop the direction of prevention and treatment of Helicobacter pylori infection-eradication therapy, which is a complex of drugs that are actively fighting the toxins of this germ and contribute to the normalization of the pH of the gastrointestinal tract that ultimately leads to the complete evacuation of bacteria.

the scheme of eradication therapyRegimens of H. p.

Eradication therapy affects both directly on the pathogen, and the results of its pathogenic action. This is due to its components: antibiotics kill bacteria, and proton pump inhibitors reduce the acidity of the stomach and duodenum, preventing the development of ulcers and, thus, creating unsustainable for microbe conditions. And as eradication therapy in his scheme contains several antibacterial agents, it is also recommended taking a probiotic drugs to prevent the development of dysbiosis. Currently, medical scientists have developed two basic schemes of the destruction of H. p. So, a three-component eradication therapy is a complex of two antibiotics (clarithromycin + amoxicillin/metronidazole) and proton pump inhibitor (drugs such as "Omeprazole," "Rabeprazole", "Pantoprazole", etc.) in standard doses twice a day. Inefficient it may be only in two cases: if the patient does not comply with the rules of the medication, or if there is resistance it a strain of H. p. one of the antibacterial agents.

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eradication therapy of peptic ulcerIn the above case is assigned a four-part scheme of eradication therapy, which additionally includes bismuth dicitrate – anti-ulcer drug with high activity against H. p. the aim of its destruction in the mucosa. This drug has a limited controlled application due to its toxic effect on the Central nervous system in the case of long-term use in high doses, because bismuth has a property of accumulating in the nervous tissue and causes drug encephalopathy. However, eradication therapy peptic ulcer disease is an integral component of treatment, because you first need influence on the etiology of the disease.


Article in other languages:

AR: https://tostpost.com/ar/health/9317-h-pylori.html

BE: https://tostpost.com/be/zdaro-e/16686-helikobakter-eradikacionnaya-terap-ya.html

DE: https://tostpost.com/de/gesundheit/16696-helicobacter-pylori-und-eradikationstherapie.html

ES: https://tostpost.com/es/la-salud/16703-helikobakter-y-eradikacionnaya-terapia.html

HI: https://tostpost.com/hi/health/9323-h-pylori.html

JA: https://tostpost.com/ja/health/9323-the-h-pylori-and-eradication-therapy.html

KK: https://tostpost.com/kk/densauly/16687-helikobakter-zh-ne-eradikacionnaya-terapiya.html

PL: https://tostpost.com/pl/zdrowie/16668-helicobacter-i-eradikacionnaya-terapia.html

PT: https://tostpost.com/pt/sa-de/16667-helicobacter-e-eradikacionnaya-terapia.html

TR: https://tostpost.com/tr/sa-l-k/16693-n-helicobacter-ve-eradikacionnaya-tedavisi.html

UK: https://tostpost.com/uk/zdorov-ya/16681-hel-kobakter-eradikac-yno-terap-ya.html

ZH: https://tostpost.com/zh/health/10158-the-h-pylori-and-eradication-therapy.html






Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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