Drug "Doxycycline", the analogues and their effects.

 "Doxycycline" refers to antimicrobial agents for systemic    applications. As the "Doxycycline" of the analogs of this drug  the funds belong to the group of tetracyclines. They have range enough  wide  actions aimed at fighting germs.

The Most famous of the drug "Doxycycline" counterparts – “Yunidoks Solutab”, “Doxycycline hydrochloride”, “Doxybene”, “Doxycycline-Darnitsa" and some others. Quite often you can observe how one thinks, what to buy, "Doxycycline” or “Yunidoks”, for example. It should be noted that the pharmacodynamics of these drugs are the same. So, they are all active against gram-positive (Stamphylococcus spp. Streptococcus spp., Actinomyces Israeli, Clostridium spp., Listeria monocytogens, Bacillus anthracis) and gram-negative (Neisseria gonorrhoeae, Vibrio cholerae, Bordetella pertussis, Yersinia spp., Enterobacter spp. Klebsiella spp., Escherichia coli, Salmonella spp., Shigella spp.) mikroorganizmov. Sensitive to "Doxycycline" and its analogues Mycoplasma spp. Rickettsia spp. Treponema spp., Borrelia burgdorferi, Chlamydia spp., some protozoa (including Entamoeba histolytica, Plasmodium falciparum). Most sensitive to peers "Doxycycline" Haemophilus influenza (91-96%) and intracellular pathogens.

The Only significant detail that differs from the drug "Doxycycline" counterparts – is that he is less other means tetracycline worsen the intestinal flora, and is more lasting, and more complete absorption. Antibiotics several tetracyclines penetrate cells and inhibit the reproduction of pathogens located there. The degree of bacterial activity, the drug “Doxycycline hydrochloride” ahead of all the other tetracyclines, including natural.

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As the drug "Doxycycline" analogues of it have the following indications for use:

- infeccao otolaryngology;

infection of the respiratory tract;

infection of the genitourinary system;

infection of the soft tissues and skin;

infection of the biliary tract and the gastrointestinal tract;

osteomyelitis, brucellosis, pertussis;

-syphilis, yersiniosis, malaria, yaws, fever, legionellosis, typhoid, rickettsiosis, Lyme disease, chlamydia various localization, bacillary and amoebic dysentery, cholera, tularemia, actinomycosis;

- part of the overall therapy – granulocyte erlihioz, leptospirosis, psittacosis, trachoma, psittacosis;

- subacute bacterial endocarditis, sepsis, peritonitis.

No "Doxycycline" with a strong sensitivity to tetracyclines, severe liver failure, porphyria, during pregnancy, lactation (for the period of the drug from breast-feeding should be abandoned), the age of children to 12 years. With caution should take this drug to people who have disorders of the liver, leukopenia.

The Drug "Doxycycline" can have adverse effects on:

- the nervous system (the effect of toxins on the Central nervous system, intracranial pressure above normal);

- the organs of hearing (ears noise appears);

- the digestive system (enterocolitis, vomiting and nausea, diarrhea or constipation, gastritis, dysphagia, glossitis, esophagitis, expression of gastric and 12 duodenal ulcer);

- from the cardiovascular system (edema, tachycardia);

- the organs of hematopoiesis(thrombocytopenia, eosinophilia, hemolytic anemia, neutropenia, porphyria);

reactions that would indicate allergies (skin flushing, pruritus, anaphylactoid reactions, maculopapular rash, Stevens-Johnson syndrome, swelling antiholetsaticeski);

- other (hepatitis, jaundice, myalgia, arthralgia, photosensitivity, strong color change of tooth enamel, inflammation of the anogenital area, candidiasis, dysbiosis).

Overdose "Doxycycline" you may notice the following symptoms: hepatotoxicity, more pronounced side effects. In this case, you should immediately resort to medical help, stop the drug and to conduct a symptomatic therapy (because there is no specific antidote), it is also necessary to support and to control how the flow of the vital functions.