"Amoxil": user manual, description of the drug, indications, contraindications, counterparts

Among a large number of antibiotics a few stand out properties such as a wide range of effects. The drug "Amoxil", reviews of which indicate its effectiveness against most pathogens, among this kind of drugs. That's about it, and will be discussed in this article.

Description of the drug: release form, composition

Means "Amoxil" produced in tablet form for oral administration with a content of active ingredient (semi-synthetic amoxicillin) 250 and 500 mg. Pills of valium have a rounded shape with line on one side and beveled edges. Their color ranges from white to slightly yellowish. Tablets at a dosage of 250 and 500 mg are Packed by 10 pieces in the contour of the package (blisters), which are placed in cardboard boxes. Each box contains two contour packaging of tablets, as well as the instructions for use of the drug. Tablets dosage 625 mg are Packed in blisters of 7 cells, which are also placed in cardboard boxes.

Storage Conditions and supply of pharmacies

According to the instructions for use, tablets "Amoxil" are dispensed from pharmacies only by prescription. The permissible period of use of the drug is limited to two years from the date of production. It is necessary to pay attention to the conditions in which were kept the tablets. The drug "Amoxil" manual advises to keep in a cool room where the temperature does not exceed 25 degrees. Should ensure that direct sunlight did not fall for the packaging of pills, as it can cause several unwanted reactions which will lead to the loss of medicinal properties. You cannot use pills that were stored in improper conditions. The drug after expiry date must be disposed of.

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Pharmacological properties of the drug

As mentioned above, the drug “Amoxil” – an antibiotic with a broad spectrum of action. According to the group affiliation of it refers to aminopenicillins. What is the feature of exposure of bacteria this substance? The fact that the amoxicillin under the influence of several factors disintegrates, resulting in a compound that is able to inactivate certain enzymes and structures in pathogenic microorganisms and to suppress the regeneration and formation of cell walls.

The Cure "Amoxil" shows activity against pathogens such as gram-positive and gram-negative cocci and rods, anaerobic and microaerophilic streptococci, spirochetes and chlamydia. According to laboratory data, the drug is no efficacy against the fungi, Plasmodium, amoeba, mycobacteria, viruses and Mycoplasma.

The drug "Amoxil" digested fast enough. The concentration of the active substance in the blood reaches a maximum within 2 hours after receiving funds. Amoxicillin is found in tissues of the liver and gallbladder, skin, subcutaneous tissue, muscle fibers, and perinatal synovial fluids and pus. It was found that the drug has a low degree of coupling with the protein (about 18%).

The half-life of the drug from the body is 2-4 hours. The bulk of the drug (not less than 60%) is excreted through the urine unchanged.

When to take pills "Amoxil"

The Drug instructions for use recommends in infections, provoked by the activity of microorganisms, which revealed sensitivity to amoxicillin. The drug "Amoxil" (500 or 250 mg) helps to cope with the following problems:

• Sinusitis, tonsillitis and otitis media of bacterial origin;
• Bacterialike infections of the gastrointestinal tract, including those caused by Helicobacter pylori;
• Pneumonia and bronchitis of bacterial origin;
• Infections of the urinary organs, including gonorrhea, pyelonephritis, cystitis;
• Infection of the soft tissues and skin due to trauma, surgical intervention.

In addition, the drug is widely used in the postoperative period to reduce the likelihood of infection.

It's also Worth remembering that the tablet "Amoxil" of the manual recommends that after consultation with your doctor, because the lack of preparation of existing pathogens may lead to a worsening of the patient's condition.

Contraindications

In the list of contraindications to the use of the drug "Amoxil" is primarily a hypersensitivity to amoxicillin and other components of the tablets. Also, do not use this drug to persons with a diagnosis of “all” and “infectious mononucleosis”. Unsafe is the drug "Amoxil" for children up to three years. It is also not recommended to take the drug to women during lactation.

Dosage and methods of treatment "Amoxil"

Dosage of antibiotics is solely governed by medical conditions, the number which, in addition to the condition of the patient, the type and form of the disease, include such indicators as the degree of destruction of the body and the individual response of the patient to the drug, age and body weight. Apply it to the drug "Amoxil". How to take this medicine? There is no standard regimen and dosing of the drug, depending on age and body weight of the patient. So, consider the rules of the drug.

Children ages 3 to 10 years, according to the instructions, the pills must be taken two times a day, 375 mg “Amoxil". According to the testimony of the drug may occur three times a day 250 mg. Thus, the daily dose for this age group is 750 mg of amoxicillin.

For children aged 10 years recommended daily dose is 1000-1500 mg "Amoxil" (500-750 mg twice a day or 375-500 mg three times a day). This dosage is applicable for adult patients with mild-to-moderate degree of development of the disease.

In the chronic form of the disease (relapse) adult patients: the drug is administered in a dosage of from 2250-3000 mg / day (divided into three doses). Children with chronic diseases the dosage calculated based on body weight: daily dose is 60 mg of drug per kilogram of weight of the child (the total amount divided into three doses per day).

In a number of diseases require adjustment of the dosage of the drug "Amoxil". Instruction on this subject contains the following remarks:

1. When impaired renal function (KK 15-40 ml/min) requires an increase in the interval between meals at least up to 12 hours. In more severe cases, when KK reaches 30 ml/min, the daily dose should not exceed 1500 mg. time-span of 12 hours between doses should also be respected.
2. Anuria is a significant reason for the decrease in the daily dose to 2,000 mg. it is recommended to take pills three times a day.

Before prescribing this drug, it is recommended to conduct all the necessary research to identify factors that may play a role in determining dosage.

Adverse reactions overdose

While taking the drug "Amoxil" can different probability to develop adverse reactions on the part of some authorities. Most patients often suffer from dysbiosis and candidiasis of the intestines, which are expressed in violation of process of digestion, excessive gas, diarrhea and nausea. From the nervous system may also develop conditions such as hyperactivity and dizziness. Often patients suffer from itchy skin and other manifestations of allergic nature (urticaria, angioneurotic edema).

Following the disruption of the body while taking the drug "Amoxil" reviews of doctors Mention very rare:

• From the digestive system: hemorrhagic or pseudomembranous colitis;
• With the skin: vasculitis allergic origin;
• From the urinary organs: nephritis (interstitial), crystalluria;
• The part of the blood: hemolytic anemia, leukopenia and thrombocytopenia.

Sometimes patients taking the drug can develop diseases such as Stevens-Johnson syndrome, candidiasis of the mucous membranes of the oral cavity or genitals, hepatitis and erythema multiforme.

At the onset of symptoms indicating the adverse reactions, you need to temporarily stop taking the drug and consult your doctor.

Interaction with other drugs

Often the drug "Amoxil" we have to in combination with other drugs. What it may lead? This you can find below the table.

In the appointment of any drug during treatment with the drug "Amoxil" is recommended to put notify the attending physician. This will help to avoid some complications.

Special instructions

During the treatment of diseases of the drug "Amoxil" the manual recommends to maintain the urine output is normal, as there is a likelihood of crystalluria. In order to avoid this phenomenon, the patient should drink increased amount of fluids throughout the course of therapy.

Amoxicillin is in contact with the tooth enamel to change its color. To avoid negative consequences it is recommended to maintain good hygiene of the oral cavity during administration of the drug. This especially applies to children, as they often chew the tablets.

Long-term treatment with the drug "Amoxil" may trigger the development of pathogens resistant to its active substance. The same effect can occur and repeated treatment of the disease this drug. The most serious consequence of this phenomenon is the development of superinfection.

During pregnancy, the drug "Amoxil" (the analogs of the main active substance also fall under these guidelines) shall be appointed only if the benefit to the expectant mother is much higher than the risk to the fetus.

During treatment, medication is not recommended for operating heavy machinery and vehicles, as adverse reactions from the nervous system in the form of dizziness or lethargy are quite common.

Feedback about the preparation

The Reviews about the drug "Amoxil" received from the doctors, and do not have negative connotations. The only thing, on what experts pay attention to – many additional factors that can affect the development of side effects during treatment with this drug. In addition, physicians noted a high level of effectiveness of a drug even in the presence in the organism of patients of multiple pathogens.

Patients also speak positively about the pills. What do they most like or dislike about the drug "Amoxil"? The price of medicines by consumers is regarded as available (from 120 roubles for one pack). Besides the great cost of drugs, consumers say that when drug treatment is often develop goiter. Especially often the disease experienced by those patients who took the drug for a long time and in large doses.

Analogs pills "Amoxil"

Today the pharmaceutical market offers several analogues of the drug "Amoxil". The price of these medicines in most cases the same as that of the drug, referred to in this article. Often, however on drugstore shelves meet identical in composition tablets that are more expensive. In some cases, these drugs can replace the appointed doctor "Amoxil". The counterparts must contain the same active substance-amoxicillin. It is necessary to pay special attention, because if you are prescribing medication the attending physician took into account the type and type of infection present in the patient. Analogs pills "Amoxil" of the active substance are the drugs “Amoxiclav”, “the store for help”, “flemoksin soljutab” and “Amoxicillin”.