All about enzyme pepsin

Date:

2018-04-04 13:10:19

Views:

1651

Rating:

1Like 0Dislike

Share:

Table of contents:

In this article we will focus on the essential enzyme in the stomach every mammal, including humans. Be considered General information on the enzyme pepsin, information on the isomers and the role of substances in the digestive processes.

General idea

First, let's find out to what class of enzymes include pepsin. This will allow a deeper understanding of the topic.

The Enzyme pepsin belongs to the hydrolase class of proteolytic and produced by the mucous membrane of the stomach, and its main task is the splitting of proteins received with food, to peptides. Pepsin - enzyme that breaks down proteins in an acidic environment. It is produced by organisms are all mammals and reptiles, the representatives of the class of birds, and many fishes.

enzyme pepsin

Presented an enzyme refers to a protein of the globular type has a molecular weight of approximately 34,500. The molecule itself is presented in the form of the polypeptide chain and consists of three hundred and forty amino acids. In its composition also contains HPO3 and three ties disulfide nature.

rennet pepsin

Pepsin is widely used in the treatment and cheese production. In laboratories it is used for a more detailed study of protein compounds, namely, primary protein structure. Pepsin is a natural inhibitor – pepstatin.

Variety of enzyme

Pepsin has twelve isoforms. The differences between all the isomers of pepsin are electrophoretic movement skills, inactivation conditions of proteolytic activity. The cipher of pepsin-KF 3. 4. 23. 1.

The human gastric juice contains seven kinds of pepsin, and five of them diverge sharply in some qualities:

1. Actually pepsin (A) has a maximum activity in the medium of pH = 1.9, while increasing to 6 inactivated.
2. Pepsin 2 (C) maximally active in the environment of pH = 2.1.
3. Type 3 manifests the highest degree of activity at pH = 2.4-2.8.
4. Type 5, also known as gestrichen has a higher degree of activity at pH = 2.8-3.4.
5. Type 7 at pH = 3.3 to 3.9 has the highest activity.

Recommended

"Knowledge is light and ignorance is darkness": the value, meaning and alternatives

There are some sayings that would seem to need no explanation, such as “teaching & ndash; light and ignorance – darkness”. But some still do not understand their meaning. But not only for such people is written by our article. I...

What was invented by Mendeleev for the army. The history and fate of the invention

What was invented by Mendeleev for the army. The history and fate of the invention

D. I. Mendeleev was a brilliant Russian scientist-polymath, who made many important discoveries in various fields of science and technology. Many people know that he is the author of “Fundamentals of chemistry" and the periodic law of chem...

The origin of the Slavs. The influence of different cultures

The origin of the Slavs. The influence of different cultures

Slavs (under this name), according to some researchers, appeared in the story only in 6 century ad. However, the language of nationality bears the archaic features of the Indo-European community. This, in turn, suggests that the origin of the Slavs h...

Importance of the enzyme in digestion

Gastric Pepsin secreted by glands in the deactivated form (pepsinogen) and the enzyme activates hydrochloric acid. Under its influence he goes into a workable form. A mandatory condition for activity of the enzyme pepsin is the presence of an acidic environment, which is why the transition of pepsin in the duodenum it loses its activity, as in the intestinal environment alkaline. The enzyme pepsin is one of the key roles in digestion of the whole class of mammals, in particular humans. This substance breaks down food proteins into smaller peptide chains and amino acids.

Men and women the indicators of development of this enzyme are different. In men stands about twenty-thirty grams of pepsin per hour, while the woman - twenty to thirty percent less. Basic cells, designated the production of pepsin, emit it in the form of pepsinogen. After cleavage of some peptides with N-pepsinogen becomes active form. The catalyst in this reaction chemical transformations acts hydrochloric acid. Pepsin has proteazami and peptidase properties and is responsible for the disaggregation of proteins.

Medical care

pepsin enzyme breaks down proteins in acid medium

In medicine pepsin is widely used as a medicine in some diseases associated with the lack of production of this enzyme in the stomach of the patient. Extract rennet pepsin from porcine mucous membranes of the stomach. The drug is available in tablet form, placed in the blisters, with a mixture of aldina or in the form of powders. Pepsin is included in the composition and some compound medicines. Has the PBX code А09АА03. An example of a pathology in which painosalama prescribed medications, is menetrier disease.

Bovine pepsin is…

Rennet pepsin beef – one of the famous and most commonly used forms of this substance. The enzyme is produced in the fourth stomach of a calf. The drug is used in the production, formed by two enzymes: pepsin and natural pimozidom in proportional quantities. Rennet is used in cheesemaking, and its main functions - formation of clot in milk, and the participation in the process of ripening of cheese and cheese products.

rennet pepsin bovine

Bovine pepsin secreted from the stomach of cattle and in the manufacture of products for sale, goes through two stages of purification of the enzyme from the fat and impurities that are insoluble. The process of production of bovine pepsin has several stages: the extraction process, the salting-out and freeze-drying.

Other uses

The Enzyme pepsin is added to ferment. Also it is used in cheese making. Rennet is a pepsin paired with pimozidom forms the enzyme used to minimize the milk.

what class of enzymes include pepsin

The Process of folding it is called milk protein coagulation, andthat is casein, with the formation of gel on milk basis. Casein has a specific strucure, and only one peptide bond is responsible for the enzymatic type of coagulation of the protein itself. The complex of pepsin with pimozidom is actually responsible for the breakup of the relationship and leads to cuts in milk.

Conclusion

Summing up, we can say that it is a biological active substance is one of the most important enzymes involved in the digestion of food in the stomach of the representatives of many classes of living beings. In manufacturing and medicine, the substance is mainly used as medicine and added to rennet for the production of dairy and cheese products.


Article in other languages:

AR: https://tostpost.com/ar/education/7892-all-about-enzyme-pepsin.html

BE: https://tostpost.com/be/adukacyya/14078-use-pra-ferment-peps-n.html

DE: https://tostpost.com/de/bildung/14079-alles-ber-das-enzym-pepsin.html

ES: https://tostpost.com/es/la-educaci-n/14086-todo-sobre-la-enzima-pepsina.html

HI: https://tostpost.com/hi/education/7897-all-about-enzyme-pepsin.html

JA: https://tostpost.com/ja/education/7895-all-about-enzyme-pepsin.html

KK: https://tostpost.com/kk/b-l-m/14081-barly-pro-ferment-pepsin.html

PL: https://tostpost.com/pl/edukacja/14072-wszystko-o-enzym-pepsyn.html

PT: https://tostpost.com/pt/educa-o/14066-tudo-sobre-a-enzima-pepsina.html

TR: https://tostpost.com/tr/e-itim/14083-t-m-pro-enzim-pepsin.html

UK: https://tostpost.com/uk/osv-ta/14078-vse-pro-ferment-pepsin.html

ZH: https://tostpost.com/zh/education/8625-all-about-enzyme-pepsin.html






Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

Comments (0)

This article has no comment, be the first!

Add comment

Related News

Archangel Cathedral of the Moscow Kremlin: description, history and interesting facts

Archangel Cathedral of the Moscow Kremlin: description, history and interesting facts

For centuries the Russian princes thought of the Archangel Michael, defeated Satan and guarding the gates of the garden of Eden, the patron of their troops. Each time, going camping, they served him a prayer. That is why in the mi...

The structural features of the columnar cells of the tissue. Palisade (columnar) tissue of leaf blade of plants

The structural features of the columnar cells of the tissue. Palisade (columnar) tissue of leaf blade of plants

Differentiation of cells and tissues plays an important role in the development of the body. The division of responsibilities for each cell can be compared with the division of labor in the factory: if each unit only performs its ...

The passive voice in English: essence, rules of education, the methods of translation

The passive voice in English: essence, rules of education, the methods of translation

the Passive voice in English is quite a simple subject to learn, if before was well-studied methods of education of the second sacrament, especially the table of irregular verbs.What is passive voice?In English it is used very act...

Commune - a combined team

Commune - a combined team

the Commune is a collective of people rallied for cohabitation on the basis of community of property and labor. Created in the one-time rush of people, this community tries to be an example for the whole state, showing his ideal i...

Levels of organization of living nature

Levels of organization of living nature

Life on Earth was born for a long time. It originated under the influence of various complex factors, which over time has led not only to the emergence of life and its manifestation in different forms. So, the complexity of the fo...

Fundamentals and characteristics of primitive society

Fundamentals and characteristics of primitive society

the First society in human history is considered to be the primitive or pre-state. It replaced apes. What's different about the new organization? What are the signs of primitive society? Is there a background state? Will try to re...