Seronegative rheumatoid arthritis: symptoms, treatment, predictions


2018-03-17 11:51:28




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Rheumatoid arthritis is called an autoimmune disease that is accompanied by damage to connective tissue elements of the body and manifests with polyarthritis of unknown etiology. The disease was severe in its course and characteristics of therapy. Pathology has several varieties, one of which is rheumatoid arthritis seronegative.

seronegative rheumatoid arthritis

Characteristic differences of the form

In the period of the disease in the blood serum of patients with rheumatoid arthritis present specific marker, rheumatoid factor. It's the antibodies that the body produces on its own tissues. The factor has the ability to bind to an antigen of the organism.

Rheumatoid arthritis seronegative is characterized by the fact that the patient has such a factor is missing, but this does not affect the progression of the disease. The disease begins not as prevalent as other forms, and the course and symptoms are less pronounced.

The Beginning of manifestation begins with destruction of one or several joints, but they are not characteristic of the symmetry. Large joints are involved in the process more often the joints of the fingers - less.

rheumatoid arthritis seronegative


Seronegative rheumatoid arthritis, the prognosis is more favorable in comparison with other forms of pathology that develops against the backdrop of the impact of the following factors:

  • Genetic predisposition;
  • Heavy ecological situation in their living conditions;
  • Viral diseases;
  • Diseases of the endocrine system;
  • Stressful situation;
  • Mechanical damage to the components of the musculoskeletal system;
  • Allergic reactions;
  • Infectious diseases
  • Hypothermia.

The risk groups include older people (40 years). Interesting point about long-term breastfeeding: lactation up to two years reduces the likelihood of developing the disease three times.


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Clinical picture

Consider, as it progresses seronegative rheumatoid arthritis. The symptoms begin with the fact that there is discomfort and soreness in the region of one of the joints. Patients complain of a feeling of stiffness in the morning, elevated body temperature, chills, weakness.

seronegative rheumatoid arthritis prognosis

If the constraint is expressed clearly and primarily occurs defeat small joints, this suggests that the type of disease seropositive. Seronegative rheumatoid arthritis is characterized by the pathology of major joints, for example knee or hip. Pathology one joint is called monoartrit.

In addition, the patient exhibits the following symptoms:

  • The increase in regional lymph nodes;
  • Reduction of body weight;
  • Muscular atrophy;
  • Kidney disease.

From the joints as the condition progresses you can define the following:

  • The fibrous nature of the changes;
  • The presence of contractures;
  • Frequent exacerbations of the disease;
  • Dysfunction of joints;
  • One-sided localization of damage for the first year;
  • In the future, the process involves the small joints.

Stage of disease

For seronegative rheumatoid arthritis has 4 stages:

I stage - development of osteoporosis in the joint. Bone density decreases with a further decrease of their salinity.

Stage II - there is a narrowing of the joint space connecting to.

Stage III - bone covered with erosions.

IV stage - the defeat of the joint progresses until complete immobilization.

Diagnostic Methods

After examination, the doctor assigns a common clinical tests. Analysis of peripheral blood identifies the presence of inflammation in the body: increased rate of erythrocyte sedimentation and leukocytosis. In the leucocyte count observed increase in the number of band neutrophils.

seronegative rheumatoid arthritis symptoms

The Response Waaler-rose - specific method of diagnosing the presence of rheumatoid factor. The absence of the latter in blood serum confirms rheumatoid arthritis seronegative.

Next, the patient undergoes x-rays, which defines the following pathology:

  • Slight deformation of the feet;
  • The prevalence of ankylosauria;
  • Osteoporosis;
  • The initial changes in the wrist joint.

Features therapy

Treatment of seronegative rheumatoid arthritis should be comprehensive and consist of drug therapy, dieting, physiotherapy and therapeutic physical training.

Drug treatment occurs in two stages. To start eliminate the symptoms. If the patient is tormented by fever and chills, the doctor prescribes antipyretics. The best option would be a number of ibuprofen, which not only suppresses fever, but also has anti-inflammatory action.

treatment of seronegative rheumatoid arthritis

Nonsteroidal anti-inflammatory drugs also help eliminate pain and discomfort. They are applied in the form of tablets and ointments, gels for external application. From this group ispolzuut:

  • "Ibuprofen".
  • "Movalis".
  • "Dicloberl".
  • "Newmaximum".

Pain helps to stop and conventional analgesics (Analgin, "Deksalgin"), and the ineffectiveness of these two groups are using hormonal agents ("Hydrocortisone", "Dexamethasone").

Cytostatics - another group of drugs used for rheumatoid arthritis, however, the use of these medications is not always advisable, therefore, they are assigned individually in each clinical case. Representatives - "Methotrexate", "Cyclophosphamide".

In case of failure of standard treatment regimens prescribed the use of specific antibodies. This method is innovative in the field of treatment of autoimmune diseases. Introduced antibodies counteract the development of active substances that cause the development of inflammatory reactions.

Physiotherapy and physical therapy

In Parallel with drug therapy used physiotherapy methods:

  • Acupuncture
  • Laser therapy;
  • Magnetic therapy;
  • Cryotherapy

Physiotherapy exercises allow only after relief of the acute stage of the disease when there is severe pain. Physical therapy is performed alone or in a group of patients with a similar condition.

treatment of seronegative rheumatoid arthritis reviews

Use the following exercises to restore joint function:

  1. Rotational movements of the hand, arm straight and fingers clenched in a fist.
  2. Finger Movements in the horizontal or vertical projection.
  3. The thumb touches the other fingers on the hand.
  4. Small ball roll and squeeze in your palm.
  5. The Flexor and extensor movements of the elbow and knee joints.
  6. Rotational motion of the shoulder and hip joints.
  7. Mahi feet.
  8. Squats.
  9. Walking on bent legs.


The exclusive Use of folk methods of treatment will have the expected result. If the patient decided to use ointments and other home cooking, you should combine them with pharmaceutical drugs prescribed by your doctor.

There are several effective recipes that help to relieve pain and alleviate the condition of the patient:

  1. Two glasses of the kidneys lilac, pour a glass of half vodka or diluted alcohol. Infuse for 10 days in a cool dark place. Extract obtained was triturated pathological area twice a day for at least 2 weeks.
  2. Large carrots washed, peeled and RUB on a small grater. There is added turpentine and vegetable oil (5 drops each). The resulting mass is put on a gauze piece and fixed to the affected area as a compress. Perform the procedure at night is not less than 10 times. Can be alternated with compresses and applications of aloe leaf juice.
  3. A tablespoon of dry a series of pour a liter of boiling water, for half an hour to boil on a slow fire and strain. The resulting broth is added to the water for therapeutic baths.


Treatment of seronegative rheumatoid arthritis reviews, which highlight favorable predictions should include correction of the diet. Patients should limit the following Produkty:

  • Irnie;
  • Sladkie;
  • Kopchenosti;
  • Marinovannye;
  • Citrusovye;
  • Molochnye;
  • Svininu.

The diet must include sufficient amounts of fish and seafood, fresh vegetables and fruits, eggs, cereals.

seropositive seronegative rheumatoid arthritis

Unfortunately, completely cure rheumatoid arthritis seronegative impossible. Patients to end of life have to deal with the disease. But observing the expert advice scheme to the selected treatment, diet will help slow down the progression of the disease and to create conditions for the full...

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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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