Progesterone-the hormone yellow body, exerting a progestational effect. Through communication in the target organs with receptors on surfaces of cells, it enters the nucleus and stimulates RNA, activating DNA. Under the influence of progesterone the endometrium is moving from the stage of proliferation provoked by follicular hormone in the secretory phase. After fertilization, the hormone creates optimal conditions for implantation and further development of the egg (fertilized). In addition, he (progesterone) reduces the excitability and contractility of the uterine muscles and muscles of the tubes, stimulates the development of mammary gland terminal elements.
By encouraging proteinopathy increases the supply of fat and glucose utilization, increases the concentration of stimulated and basal insulin, the liver begins to accumulate glycogen, increases the production of aldosterone. Small doses of progesterone accelerates and large inhibit the production of gonadotropins in the pituitary gland. Aktiviziruyutsya growth in the mammary glands secretory atinusov Department, induced lactation, to stimulate the normal development of the endometrium.
Drug "Progesterone": injections. Manual
The Drug is indicated in amenorrhea, endocrine infertility (including in case of insufficiency of yellow body), anovulatory metrorrhagia, threatened abortion. Progesterone (injections) are also shown in algodismenoree (compared to gipogenitalizme), oligomenorrhea, the diagnosis of the formation of endogenous estrogens.
Intramuscularly administered for bleeding on the background of dysfunction of ovaries on a daily basis from five to fifteen mg. the Treatment lasts six to eight days.
If it was produced by scraping of the uterine lining, injection begins at the expiration of eighteen to twenty days (in case of impossibility to carry out the scraping administration produced when bleeding). While treatment may temporarily increased bleeding (in three-five days), after cessation of therapy continuing for another six days. If after the specified period, the condition is not relieved, further use of the drug is impractical.
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When gipogenitalizme amenorrhea and drug "Progesterone" (injections) are administered daily at 5 mg or every other day at 10 mg. Therapy is six to eight days (after use of estrogen drugs).
Treatment for algodismenoree starts before the onset of menstruation for six to eight days. Daily administered at 5 or 10 mg, and so for six to eight days. If the specified disease is caused by underdevelopment of the uterus, use estrogen (10 thousand units a day for two to three weeks), then during the six-day-cure "Progesterone" (injections).
During therapy or to prevent starting and of threatened miscarriage on the background of insufficiency of yellow body the drug is administered daily twelve and a half milligrams for two weeks from the date of ovulation (if necessary – to the eleventh week of gestation).
In the diagnosis of the formation of endogenous estrogens administered once 100 mg.
Throughout the duration of the drug "Progesterone" (injections) are recommended with caution to engage in activities related to high concentration of attention and quickness of psychomotor reactions.
The Drug can reduce the intensity of the impact of drugs that stimulate the smooth muscles in the uterus, anabolic steroids. Simultaneous administration of barbiturates reduces the effect of the drug "Progesterone".
Withdrawal of the drug should be gradual. The use of medication monitored by your doctor. The specialist should inform the patient of possible adverse events and contraindications for the drug.
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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."
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