"ACT-HIB" (the vaccine): instructions for use. The vaccine against HIB infection


2018-12-12 17:00:44




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Today one of the most significant threats to the health of young children is Haemophilus influenzae (HIB). It is developing very quickly and could entail heavy consequences, including death. Therefore, recently in our country, children and some adults is injected through injection preventive drug – "ACT-HIB" (vaccine). Russia has included it in its vaccination calendar only in 2011.

Hib vaccine is a Russian

What is Haemophilus influenzae?

The Bacteria that cause Haemophilus infection is called Haemophilus influenzae, or wand Afanasyev-Pfeiffer. There are 6 varieties of this sticks, but the most dangerous is the wand type b. It causes severe disease and further complications. Approximately 85% of adults and 35-40% of children are carriers of Haemophilus influenzae. Quite a high figure, but this is not surprising as Haemophilus influenzae belongs to the category of conditional pathogens, so its presence in the body in small amount is considered normal.

The Highest percentage of carriers of HIB infection is observed in kindergartens, approximately 5%. This disease is airborne, so the risk of Contracting in public areas is quite high. In kindergartens, this infection can be transmitted through household items: dishes, towels and toys. The severity of the disease depends on the number of bacteria ingested. For the relatively small man becomes just a carrier, with a large contact begins to develop the disease. Although wearing the infection goes unnoticed, the slightest weakening of the immune system immediately make himself known serious infectious disease.


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Hib vaccine

Haemophilus infection is most common in children from six months to 5 years. The most dangerous age for the development of this disease is from 6 to 12 months, so the drug "ACT-HIB" (the vaccine) in this period are especially needed.

What is the danger of Haemophilus influenzae?

"ACT-HIB" (the vaccine) for a reason highly recommended by pediatricians, because infection with a weakened immune system can cause a number of serious complications, such as:

  • Meningitis - it causes serious brain damage, the percentage of fatal outcome of this disease compared to other high, it is 15%;
  • Epiglottitis - the disease can lead to asphyxia, that is suffocation;
  • Pneumonia - this disease, caused by Haemophilus infection is distinguished by a particularly heavy flow and a high percentage of death;
  • Sepsis - although it occurs infrequently but has serious consequences;
  • Bronchitis - not so dangerous as pneumonia, but is fraught with transition in the chronic form;
  • Otitis media - with severe course facing partial deafness.

Hib vaccine manual

This is not to mention the fact that HIB infection is becoming a cause of acute respiratory infections and arthritis. The insidiousness of Haemophilus influenzae is that the initial symptoms in most cases does not cause anxiety in parents. Clinical signs usually become apparent at the onset of complications. Wand type b are particularly resistant to antibiotics, therefore, cause many difficulties in the treatment of Haemophilus influenzae infection (HIB). The vaccine does not guarantee that a child will not develop, but will help to ease the disease.


"ACT-HIB" (the vaccine) produced by the French company "Sanofi Pasteur". It was registered in Russia in 1997 until 2010, the vaccine against HIB infection, was put on a voluntary basis. Only at the end of 2010, due to the high percentage of morbidity was included vaccination calendar on a legal basis.vaccine against Hib infection

"ACT-HIB" vaccine, reviews of which are highly controversial. However, she urged parents with children under the age of 5 years. This is especially true of kids that fall into the following risk groups:

  • Premature babies;
  • Children who are bottle-fed;
  • Children with weakened immune systems, prone to frequent colds;
  • Kids with chronic illnesses which their body can't fight infections;
  • Children who attend public educational institutions.

"ACT-HIB" (vaccine) is pricked not only children but also adults suffering from immunodeficiency.

How does the vaccine?

Haemophilus drug created on the basis of defective antigen attached to the protein molecule of tetanus toxoid. It does not contain the bacteria Haemophilus influenzae type b and therefore cannot cause disease. The combination of antigen with protein have solved several problems:

  • The children had formed a strong immunity to bacteria;
  • Resulting in reduced reactogenicity of the vaccine and make it safer.

Haemophilus influenzae vaccine compared with their counterparts, and their two - vaccine "Hiberix" and "Pentax", has passed more clinical trials whose results are more than satisfactory. It was found that the immunity generated in a child lasts for 4 years. This period is enough, since in the fifth year of life the baby begins to produce the right amount of antibodies against HIB infection.

This kind of vaccination involves notonly personal protection against infection, but also strengthens collective immunity. Ongoing studies have shown that in preschools through vaccination, the morbidity rates have been reduced from 40 to 3.


The Vaccine "ACT-HIB" instruction for the use of which is familiar to every physician, is kids, starting at two months of age. If the initial vaccination done in the first six months of a child's life, the diagram looks like this:

  • The first time vaccination is done at a fixed time;
  • Second time - re-vaccination is carried out 30-45 days;
  • Third time - the last vaccination is appointed a year after the first.

Haemophilus Hib vaccine

If the first vaccination was delivered in the second half of the year, the scheme is changing accordingly, i.e. it loses one step and vaccination is made with an interval in 1 month. If vaccination is done after a year, only 1 injection.

"ACT-HIB" vaccine, the statement of which requires strict compliance with the regulations. The injection is made intramuscularly or subcutaneously. Kids under the age of 2 years, the injection is introduced into the front part of the thigh, older children - in the shoulder, or the deltoid muscle.

Features and composition

One of the most safe and convenient injection is the vaccine "ACT-HIB". Manual, reviews of foreign and Russian doctors claim that this drug is allowed to be mixed in the same syringe with other vaccines, e.g. TDAP vaccine. The main advantages of this drug include the following details:

  • Practically no side effects, and therefore are allowed from birth;
  • Of great assistance in formulating the required number of antibodies;
  • Retains immunity for a long time;
  • Shows good result in the fight with wand type b.

HIB vaccine reviews

Haemophilus influenzae vaccine has efficacy due to included items that have high activity. This:

  • Sucrose;
  • Sodium chloride;
  • Treated water for injection;
  • Trometamol;
  • Coupling of polysaccharide and tetanus protein.

This composition enables to maintain the immune system at a proper level even in the youngest children.

Reaction to the vaccination and possible complications

"ACT-HIB" vaccine, which is quite easy to carry. In almost all cases, the immune system responds to the injection, only a small percentage of grafted reaction is insufficient. Defense mechanism to fight the disease is formed within 14 days after injection. More than 90% vaccinated population, it stays at the same level from 4 to 5 years.

Usually, the vaccine does not cause any side effects, in some cases, there may be redness, swelling or induration at the injection site. In addition, the injection may cause the following complications:

  • Swelling;
  • Itching;
  • Rash;
  • Vomiting;
  • Anxiety and prolonged crying;
  • Fever;
  • Hives;
  • Convulsions.

vaccine act Hib manual reviews

Generally, the symptoms observed by mixing the two vaccines. It completely goes away without medical intervention during the day. It should be noted that the vaccine may trigger an increase in the gap between respiratory movements in infants. This is especially true of premature babies born before 28 weeks.

Preparation for vaccination

In order to avoid complications, to the introduction of Haemophilus influenzae vaccine, like any other, need to prepare. This requires a conversation with your doctor or pediatrician and clarify all necessary information about the properties and side effects of the drug. For several days prior to vaccination it should:

  • To carry out a full medical examination;
  • Protect baby from contact with sick people;
  • If the child is fed with breast milk, the mother should not be administered in the diet of new foods - this can lead to different allergic reactions.

The Body of each person reacts to the vaccine differently. To alleviate or to avoid unexpected reactions, it is recommended that:

  • After vaccination, to remain under medical supervision for half an hour;
  • Take daily walks, but only in areas where there are large concentrations of people, the only way to prevent getting the infection;
  • The first three days to bathe the baby can be under the shower no more than 3 minutes;
  • To exclude the introduction in the diet of the baby or mom's new products.

Haemophilus vaccine can cause allergies to the individual components, so as a preventive measure you need to take drugs such as "Suprastin" or "Zodak" (doctor's advice).


According to the instructions, the vaccine is contraindicated in:

  • People with individual intolerance to components of the preparation;
  • Children with allergic reaction to the vaccine or other vaccinations;
  • Children with allergic reactions to tetanus toxoid.

For the complete assimilation of the drug components the body needs to be absolutely healthy.

Release Form and storage conditions of the vaccine

The Bottle of medicine and syringe with solution for injection comes in a thermal package. Purchasing this drug is only allowed medicalinstitutions.

vaccine act Hib instruction manual

Stored vials of vaccine in the refrigerator, the optimum temperature is 2-8 degrees Celsius. If the preparation is stored at low temperatures, it loses most of its active properties. Term use vaccine - 3 years, after which it is recycled.

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