Drug "Velopex": reviews, indications for use, dosage


2018-11-07 23:00:56




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Unfortunately, depression and other disorders are not uncommon in the modern world. Some psychological problems can be overcome independently. On the other hand, in more severe cases, the anti-anxiety meds are just necessary. Quite effective is the ‘Velofax”. Specialists and patients confirm that the drug helps to solve a lot of problems. Therefore, in modern medicine, it is used often.

Of Course, the clinic of neurosis requires appropriate measures. So that is part of the medication and how it affects the body? Is there any information about overdose? How to take the pills? This information looking for a readers.

Description of medicine. Release form

velofax reviews

This drug is available in the form of oblong tablets yellow. What substance is the main active component of the drug “Velofax”? Venlafaxine hydrochloride in the amount of 37.5 or 75 mg per tablet (in pharmacies to buy the drug with different dosage). They are placed in blister packs of 14 pieces. In the package, usually two blisters and, therefore, 28 tablets.

Of Course, the product contains additional components, in particular talc, magnesium stearate, iron oxide yellow (colorant), carboximetilkrahmal sodium, corn starch and microcrystalline cellulose.

What are the pharmacological properties of the drug?

This drug belongs to the group of antidepressants. The active substance can affect the Central nervous system, potenziruet the transmission of nerve impulses. The drug is quite potent reuptake inhibitor of norepinephrine and serotonin. However, it lowers the beta-adrenergic reactivity, and this effect may be observed both after a single dose and during long-term therapy. Active components of the drugs do not affect the process of release of norepinephrine from brain tissue.


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This drug is pretty well absorbed by the walls of the gastrointestinal tract. The maximum concentration of active substance in the blood ranges from 25 to 150 mg. These values are observed 2 hours after ingestion. By the way, if to drink a pill during or before a meal, then the maximum effect will be observed for 20-30 minutes later.

Active substance is bound to plasma proteins approximately 27-30 %. Intensive metabolism of the drug occurs in the liver cells. The half-life ranges from 5 to 11 hours. Metabolites, as well as venlafaxine the same form, excreted by the kidneys. Gender and age of the patient did not affect the pharmacokinetics.


clinic of neuroses

Of Course, first and foremost, patients are interested in the question, in what cases it is advisable to take medication “Velofax”. Reviews of doctors, as well as the research results say that this drug is effective for depression, especially if they are associated with high anxiety.

The Drug “Velofax": usage instructions

In Any case you should not use this medicine on their own. The dosage, schedule of admission, duration of treatment can only be determined by a doctor. Here the many factors are: the clinic of neurosis, the age and General condition of the patient, taking medications, contraindications, etc.

daily dose

The Tablet is best taken before or during meals. It is impossible to chew, to swallow fully, drinking plenty of water. The drug should preferably be taken at the same time of the day. Typically, the initial dose — 37.5 mg twice a day. If the desired therapeutic effect was not achieved, the number of one-time prinimaesh of the drug increased to 75 mg twice a day. The maximum daily dose — 375 mg of the active component. Once the desired effect is achieved, you can begin to slowly reduce the dose.

Are There contraindications to therapy?

Many people today are interested in questions about how to get rid of anxiety and depression. Of course, this medicine helps to cope with problems, but there are some limitations to its method:

  • Hypersensitivity to ingredients;
  • The medicine has age restrictions, it is impossible to accept patients under the age of 18 years;
  • Pregnancy and breast feeding.
  • This medicine should not be taken together with MAO inhibitors.

In Addition, there are also relative contraindications in which the treatment is possible, but under watchful supervision. In particular, the drug is prescribed with caution in patients with tachycardia, hypertension, closed angle glaucoma, hyponatremia. In addition, relative contraindications include reduced body weight, predisposition to bleeding, manic state in the patient's diagnosis, the presence of suicidal tendencies, increased intraocular pressure.

Possible side effects?

velofax overdose

Of Course, like any other antidepressant, thisthe drug can cause some side effects. Complications are quite varied, here are the most common ones are:

  • Quite often there are violations in the digestive system, especially nausea and loss of appetite, abdominal pain, dry mouth, constipation, dyspepsia. Rarely the therapy developed pancreatitis and hepatitis.
  • Possible symptoms of the cardiovascular system, including lowering or raising blood pressure, arrhythmia, tachycardia, hyperemia skin. Occasionally develops ventricular fibrillation and tachycardia.
  • Possible metabolic disorders, for example, a decrease or a sharp increase in body mass, increases in cholesterol. Rarely on a background of reception of tablets decrease the secretion of antidiuretic hormone, increased level of prolactin.
  • Common side effects include weakness, dizziness, severe yawning, drowsiness, nightmares, hypertonicity of muscles, increased nervous excitability. To disorders of the nervous system also may include asthenia, tremor, apathy, fainting, hallucinations. Occasionally therapy leads to the development of delusions, disorders of coordination, convulsions, delirium, agitation anxiety.
  • Possible changes in the lymphatic system and blood circulation, including hemorrhagic syndrome, small hemorrhages in the skin and mucous membranes, thrombocytopenia, rarely-aplastic anepia, pancytopenia and agranulocytosis.
  • Some patients complain of problems with urination.
  • There is a possibility of disruption of the senses, which is reflected by the appearance of noise in the ears, changes in taste, problems with accommodation, a decrease in vision.
  • The Therapy can affect the quality of sexual life, causing decreased libido, erectile dysfunction, problems with ejaculation, changes in menstrual cycle, inability to achieve orgasm.
  • Tablets can cause an allergic reaction, which is accompanied by the appearance of a skin rash, redness, urticaria, edema. More likely to have erythema, anaphylactic shock.
  • There are some other adverse reactions that can occur during treatment. Sometimes patients complain of increased sweating, hair loss (occurs very rarely), severe dyspnea, pulmonary eosinophilia. Sometimes there are muscle spasms, myalgia, arthralgia.

It is Worth noting that the occurrence of side effects sometimes due to the fact that daily dose is too high. However, in other cases you may need to cancel the medication. If you notice any deterioration, you should immediately go to the doctor.

Overdose and its symptoms

how to get rid of anxietyWhat happens if you take too high a dose of the drug “Velofax”? Overdose is possible and is accompanied by characteristic symptoms. First, there is a dizziness, a decrease in blood pressure. As the penetration of active ingredients into the bloodstream develops ventricular and sinus tachycardia. Also possible seizures. Some patients have had different disturbances of consciousness, ranging from drowsiness and fatigue, ending in a comatose state. If time does not provide patient assistance, overdose can lead to death. By the way, these symptoms occur not only with increasing dose, but also when co-administered tablets with ethanol (alcohol).

With regard to therapy, in this case it is symptomatic because no specific antidote. Treatment is aimed at maintaining the basic functions of the human body and should be in the hospital.

Elimination of the drug: what to expect?

As you know, the most severe stage of therapy is the process of cancellation of antidepressant. Therefore, the daily dose is reduced gradually. Only after the amount of the used drug was kept to a minimum, it is possible to stop therapy.

The Syndrome can be accompanied by different symptoms. Some patients can experience fatigue and drowsiness. Possible asthenia, headaches, insomnia, constant anxiety, appearance anxiety, irritability, sometimes apathy, disorientation, confusion. Sometimes the patient after the cancellation of developing depression, suicidal tendencies appear.

How much is the drug?

Of Course, for many patients it is important not only features, but the cost of medicines. So how much will the drug “Velofax”? The price will depend on several factors including the manufacturer, city, financial policy, pharmacy etc packing tablets with a dosage of 37.5 mg is in the range from 480 to 560 rubles. Tablets containing 75 mg of active substance, of course, are more expensive — the numbers in this case range from 680 to 750 rubles. Of course, it is understood that sometimes completing a full course treatment you will need a few packages.

The Drug “Velofax": models and qualitative substitutes

velofax analogues

For whatever reasons, not every patient is suitable for that medicament. And to do in such cases? Is there any way to replace tablets the ‘Velofax”? The doctors showthat if necessary, the drug can be replaced. For example, instead patients sometimes take drugs such as the ‘Venlaxor” or “Dapyx”. The analogs also include the ‘Velaxin”. Of course, modern pharmaceutical market offers a huge number of antidepressants of different categories, but it is understood that you assign this tool can only be the attending physician.

Testimonials from patients and doctors about the cure

Naturally, many people are interested in the views of doctors and patients who had to undergo a course of treatment. So talking about the drug “Velofax”? Reviews for the most part are positive. Experts note that the effect of this antidepressant is almost instantaneous. Naturally, home treatment may be associated with some complications, and therefore initial dose, usually much lower. Patients say that the body gets used to the medication for a few days, then it is already possible to take without fear of serious complications.

velofax price

The advantages of medication can be attributed to the relatively affordable price, as many antidepressants are much more expensive. And to find the drug can be almost anywhere.

Unfortunately, reviews of patients also suggests that it is very difficult to stop taking this drug. The withdrawal process should be conducted under the supervision of a specialist, and should prepare for the fact that the rejection of pills take a lot of time.

In Any case it is not necessary to take the medicine voluntarily. Only a doctor knows about how to get rid of anxiety and depression. Uncontrolled use of such strong medications can lead to disastrous consequences.

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